Natural Therapy of Cutaneous Leishmaniasis

sand flies, there are ad by the bite of phlebotomine Leishmaniasis is a parasitic disease that is spre s, common forms is cutaneous leishmaniasi several different forms of leishmaniasis in people, the most ore cutaneous lesions, Cutaneous leishmaniasis is characterized by one or m and visceral leishmaniasis, usually Cutaneous leishmaniasis can change in size and appearance over time, the skin sores of which heir own, even without treatment, but this can take months or even years. A recent study has heal on t lead to new natural treatment to accelerate the healing time of lesions caused by leishmania parasite, ions site during night for seven to ten days. which based on using a bandage of banana peels at the les responded positively to using banana peels and completely cured, were eight cases out of ten have There and two did not respond. Patients who have the injection treatment is healed in short time in compare to . ne who did not take injection


Introduction
Leishmaniasis is a disease, caused by a protozoan parasite of the genus Leishmania, and transmitted by a Genus phlebotomus in the old world and the genus Lutzomyia in (1).bite of infected female sand flies the new world (2).It is Prevalent in 98 countries and regions of the world which responsible for increasing health problems (3).

Introduction
Leishmaniasis is a disease, caused by a protozoan parasite of the genus Leishmania, and transmitted by a Genus phlebotomus in the old world and the genus Lutzomyia in (1).bite of infected female sand flies the new world (2).It is Prevalent in 98 countries and regions of the world which responsible for increasing health problems (3).

Introduction
Leishmaniasis is a disease, caused by a protozoan parasite of the genus Leishmania, and transmitted by a Genus phlebotomus in the old world and the genus Lutzomyia in (1).bite of infected female sand flies the new world (2).It is Prevalent in 98 countries and regions of the world which responsible for increasing health problems (3).

Figure (1) Geographical distribution of Leishmania sp (7).
The cutaneous leishmaniases (CL) include a spectrum of self healing and chronic disease forms, the The patients Clinical presentations differ according to parasite burden and host immune response (6).
or nodule at the site of inoculation, followed by with cutaneous leishmaniasis present with a papule formation of crusts, which causes skin sores.There are various procedures and laboratory techniques used to diagnose leishmaniasis, punch skin biopsy is widely used &populartechnique(1).The diagnosis L is based on clinical features (supported by epidemiologic data) and laboratory testing, numerous of C diagnostic methods have been described with a huge variation in diagnostic accuracy, including direct and parasite culture) and/or indirect testing with parasitologic examination (microscopy, histopathology, serology and molecular diagnostics (9).Different drugs like sodium stibogluconate, sodium antimony gluconate, Amphotericin B and Miltefosine: are used for its treatment (1).Amphotericin B injection in a dose of 25 mg in 5% dextrose can be administered intravenously 6 hourly with a total dose of 1980 mg (1).Pentavalent antimonials, Intra lesional infiltration of 1-5 ml (100 mg/ml) sodium stibogluconate (SSG) can be given to patients with cutaneous leishmaniasis on alternate days for three days once a month and this results in complete healing by the end of second month in most cases (4).

Cutaneous leishmaniasis in Libya
Zoonotic cutaneous leishmaniasis, caused by leishmania .major,which is the main type of leishmaniasis in the country.The number of cases has progressively decreased since the implementation of control activities at the end of 2006 and probably also due to protective immunity in the populations affected.Control measures mainly consisted of reducing the rodent population and using vector control techniques by local pest management companies.The national control programme for leishmaniasis in Libya is well established and structured.It has managed to eliminate 85%-90% of the Psammomys population, the animal reservoir, in the targeted areas (8).

Prophylactic vaccines
There is no vaccine against leishmaniasis, although, intradermal inoculation of live virulent L. major promastigotes has been used to protect against L. major infection (5).

Control of leishmaniasis
The best way for travelers to prevent infection is to protect themselves from sand fly bites and to decrease the risk of being bitten, by Avoid outdoor activities, especially from dusk to dawn, when sand flies generally are the most active(7).The national center for disease control in Libya are doing the best to control and decrease the prevalence of leishmania parasite infections in Libya by making awareness campaigns throughout endemic area in all regions(8).

Banana peels
anana peel was able to draw attention as a source of functional and nutritional compounds, for b biological activities of banana peel as antioxidant and antimicrobial activities as a result of containing ds, tannins, saponins, glycosides, carotenoids, compounds as, Phenolic compounds, alkaloids, flavonoi sterols, triterpenes, and catecholamine.multiple e compounds, potentials, and Future studies are required to determine the biologically activ benefits hoped for banana peel instead of being a neglected waste (12).For making wound dressing, the banana part used is peel, this is because lignin affect (10).Banana helps the formation of peels compound so it can be used to treat, burns, bruises, and skin infections(11).

IJFMR230611252
Volume 5, Issue 6, November-December 2023 The cutaneous leishmaniases (CL) include a spectrum of self healing and chronic disease forms, the The patients Clinical presentations differ according to parasite burden and host immune response (6).
or nodule at the site of inoculation, followed by with cutaneous leishmaniasis present with a papule formation of crusts, which causes skin sores.There are various procedures and laboratory techniques used to diagnose leishmaniasis, punch skin biopsy is widely used &populartechnique(1).The diagnosis L is based on clinical features (supported by epidemiologic data) and laboratory testing, numerous of C diagnostic methods have been described with a huge variation in diagnostic accuracy, including direct and parasite culture) and/or indirect testing with parasitologic examination (microscopy, histopathology, serology and molecular diagnostics (9).Different drugs like sodium stibogluconate, sodium antimony gluconate, Amphotericin B and Miltefosine: are used for its treatment (1).Amphotericin B injection in a dose of 25 mg in 5% dextrose can be administered intravenously 6 hourly with a total dose of 1980 mg (1).Pentavalent antimonials, Intra lesional infiltration of 1-5 ml (100 mg/ml) sodium stibogluconate (SSG) can be given to patients with cutaneous leishmaniasis on alternate days for three days once a month and this results in complete healing by the end of second month in most cases (4).

Cutaneous leishmaniasis in Libya
Zoonotic cutaneous leishmaniasis, caused by leishmania .major,which is the main type of leishmaniasis in the country.The number of cases has progressively decreased since the implementation of control activities at the end of 2006 and probably also due to protective immunity in the populations affected.Control measures mainly consisted of reducing the rodent population and using vector control techniques by local pest management companies.The national control programme for leishmaniasis in Libya is well established and structured.It has managed to eliminate 85%-90% of the Psammomys population, the animal reservoir, in the targeted areas (8).

Prophylactic vaccines
There is no vaccine against leishmaniasis, although, intradermal inoculation of live virulent L. major promastigotes has been used to protect against L. major infection (5).

Control of leishmaniasis
The best way for travelers to prevent infection is to protect themselves from sand fly bites and to decrease the risk of being bitten, by Avoid outdoor activities, especially from dusk to dawn, when sand flies generally are the most active(7).The national center for disease control in Libya are doing the best to control and decrease the prevalence of leishmania parasite infections in Libya by making awareness campaigns throughout endemic area in all regions(8).

Banana peels
anana peel was able to draw attention as a source of functional and nutritional compounds, for b biological activities of banana peel as antioxidant and antimicrobial activities as a result of containing ds, tannins, saponins, glycosides, carotenoids, compounds as, Phenolic compounds, alkaloids, flavonoi sterols, triterpenes, and catecholamine.multiple e compounds, potentials, and Future studies are required to determine the biologically activ benefits hoped for banana peel instead of being a neglected waste (12).For making wound dressing, the banana part used is peel, this is because lignin affect (10).Banana helps the formation of peels compound so it can be used to treat, burns, bruises, and skin infections(11).

IJFMR230611252
Volume 5, Issue 6, November-December 2023 The cutaneous leishmaniases (CL) include a spectrum of self healing and chronic disease forms, the The patients Clinical presentations differ according to parasite burden and host immune response (6).
or nodule at the site of inoculation, followed by with cutaneous leishmaniasis present with a papule formation of crusts, which causes skin sores.There are various procedures and laboratory techniques used to diagnose leishmaniasis, punch skin biopsy is widely used &populartechnique(1).The diagnosis L is based on clinical features (supported by epidemiologic data) and laboratory testing, numerous of C diagnostic methods have been described with a huge variation in diagnostic accuracy, including direct and parasite culture) and/or indirect testing with parasitologic examination (microscopy, histopathology, serology and molecular diagnostics (9).Different drugs like sodium stibogluconate, sodium antimony gluconate, Amphotericin B and Miltefosine: are used for its treatment (1).Amphotericin B injection in a dose of 25 mg in 5% dextrose can be administered intravenously 6 hourly with a total dose of 1980 mg (1).Pentavalent antimonials, Intra lesional infiltration of 1-5 ml (100 mg/ml) sodium stibogluconate (SSG) can be given to patients with cutaneous leishmaniasis on alternate days for three days once a month and this results in complete healing by the end of second month in most cases (4).

Cutaneous leishmaniasis in Libya
Zoonotic cutaneous leishmaniasis, caused by leishmania .major,which is the main type of leishmaniasis in the country.The number of cases has progressively decreased since the implementation of control activities at the end of 2006 and probably also due to protective immunity in the populations affected.Control measures mainly consisted of reducing the rodent population and using vector control techniques by local pest management companies.The national control programme for leishmaniasis in Libya is well established and structured.It has managed to eliminate 85%-90% of the Psammomys population, the animal reservoir, in the targeted areas (8).

Prophylactic vaccines
There is no vaccine against leishmaniasis, although, intradermal inoculation of live virulent L. major promastigotes has been used to protect against L. major infection (5).

Control of leishmaniasis
The best way for travelers to prevent infection is to protect themselves from sand fly bites and to decrease the risk of being bitten, by Avoid outdoor activities, especially from dusk to dawn, when sand flies generally are the most active(7).The national center for disease control in Libya are doing the best to control and decrease the prevalence of leishmania parasite infections in Libya by making awareness campaigns throughout endemic area in all regions(8).

Banana peels
anana peel was able to draw attention as a source of functional and nutritional compounds, for b biological activities of banana peel as antioxidant and antimicrobial activities as a result of containing ds, tannins, saponins, glycosides, carotenoids, compounds as, Phenolic compounds, alkaloids, flavonoi sterols, triterpenes, and catecholamine.multiple e compounds, potentials, and Future studies are required to determine the biologically activ benefits hoped for banana peel instead of being a neglected waste (12).For making wound dressing, the banana part used is peel, this is because lignin affect (10).Banana helps the formation of peels compound so it can be used to treat, burns, bruises, and skin infections(11).
The banana peels also contains other substances as fatty acids, and carotenoids, which have proved antioxidant activity (12).

Material and methods
Treating leishmania infection is not hard, although it takes time to heal completely and may leave scar.Recently we have came up with trial has been successful to help and heal infection, the trial steps are very simple, it based on using banana peels nightly for seven to ten nights as bandage, based on the progress of parasitic infection, the peels of banana used directly on the lesion of leishmania infection, even, the patients who have the infection can apply the peels of banana with himself every night.Peels that have been collected, washed with water to remove dirt, and cut into small pieces and then used as bandage.Banana peels , bandage, 70% alcohol, gloves, Distilled water all are used in the trial

Result and discussion
Using banana peels on the lesion is successful method to cure leishmania parasite infection, especially if the patient had the injection treatment, as it is shown in figure (3,4) which illustrate how banana peels successful in healing the lesion jus in six days.After the trials we have done, eight cases have responded and healed completely, but two have not responded, and healed partially, by partially we mean their infection symptom have relived.The banana peels also contains other substances as fatty acids, and carotenoids, which have proved antioxidant activity (12).

Material and methods
Treating leishmania infection is not hard, although it takes time to heal completely and may leave scar.
Recently we have came up with trial has been successful to help and heal infection, the trial steps are very simple, it based on using banana peels nightly for seven to ten nights as bandage, based on the progress of parasitic infection, the peels of banana used directly on the lesion of leishmania infection, even, the patients who have the infection can apply the peels of banana with himself every night.Peels that have been collected, washed with water to remove dirt, and cut into small pieces and then used as bandage.
Banana peels , bandage, 70% alcohol, gloves, Distilled water all are used in the trial

Result and discussion
Using banana peels on the lesion is successful method to cure leishmania parasite infection, especially if the patient had the injection treatment, as it is shown in figure (3,4) which illustrate how banana peels successful in healing the lesion jus in six days.
After the trials we have done, eight cases have responded and healed completely, but two have not responded, and healed partially, by partially we mean their infection symptom have relived.The banana peels also contains other substances as fatty acids, and carotenoids, which have proved antioxidant activity (12).

Material and methods
Treating leishmania infection is not hard, although it takes time to heal completely and may leave scar.
Recently we have came up with trial has been successful to help and heal infection, the trial steps are very simple, it based on using banana peels nightly for seven to ten nights as bandage, based on the progress of parasitic infection, the peels of banana used directly on the lesion of leishmania infection, even, the patients who have the infection can apply the peels of banana with himself every night.Peels that have been collected, washed with water to remove dirt, and cut into small pieces and then used as bandage.
Banana peels , bandage, 70% alcohol, gloves, Distilled water all are used in the trial

Result and discussion
Using banana peels on the lesion is successful method to cure leishmania parasite infection, especially if the patient had the injection treatment, as it is shown in figure (3,4) which illustrate how banana peels successful in healing the lesion jus in six days.
After the trials we have done, eight cases have responded and healed completely, but two have not responded, and healed partially, by partially we mean their infection symptom have relived.Leishmania parasite infection is hard to cure in short time, especially the scar on the skin that left after healing, that scar totally disappear after using the banana on the lesion in some cases, especially if the infection in the beginning or the patient had the injection treatment, also it can help in reliving symptoms of leishmania infection such as cramping, fever and bleeding .The patients who had the leishmania parasite treatment injection is quicker to heal than one who did not take the injection, also infection in the beginning more successful to respond as it shown in the table (1) and figures (3,4).Leishmania parasite infection is hard to cure in short time, especially the scar on the skin that left after healing, that scar totally disappear after using the banana on the lesion in some cases, especially if the infection in the beginning or the patient had the injection treatment, also it can help in reliving symptoms of leishmania infection such as cramping, fever and bleeding .The patients who had the leishmania parasite treatment injection is quicker to heal than one who did not take the injection, also infection in the beginning more successful to respond as it shown in the table (1) and figures (3,4).Leishmania parasite infection is hard to cure in short time, especially the scar on the skin that left after healing, that scar totally disappear after using the banana on the lesion in some cases, especially if the infection in the beginning or the patient had the injection treatment, also it can help in reliving symptoms of leishmania infection such as cramping, fever and bleeding .The patients who had the leishmania parasite treatment injection is quicker to heal than one who did not take the injection, also infection in the beginning more successful to respond as it shown in the table (1) and figures (3,4).