Design and Development of a Lipid-Based Self-Nano Emulsifying Drug Delivery System of Rosuvastatin Calcium

Author(s)	Kethavath Bhagya, M. Sunitha Reddy
Country	India
Abstract	The work aimed at design and development of a self-nanoemulsifying drug delivery system to increase the solubility and further to evaluate pharmacokinetic parameters of Rosuvastatin calcium (SNEDDS).A unique High Performance Liquid Chromatography technique was used to measure drug concentration in albino rat blood plasma, optimized Self-Nano emulsified formulation had greater absorption than the drug suspension. Lab solutions software were used to analyse the plasma drug concentration data.
Keywords	SNEDDS, Rosuvastatin Calcium, solubility using a pseudo-ternary phase. In-vitro dissolution and in-vivo animal studies and bioavailability, HPLC analysis, UV Spectrophotometer.
Field	Medical / Pharmacy
Published In	Volume 5, Issue 6, November-December 2023
Published On	2023-12-16
DOI	https://doi.org/10.36948/ijfmr.2023.v05i06.10376

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