Review On Various Protocol To Access Imidazole And It’s Versatile Biological Activities

Author(s)	Karan C. Waghmare, Babasaheb B. Maind, Adesh V. Kharate, Gajanan Y. Shinde, Dr. Bapurao B. Shingate
Country	India
Abstract	Imidazole occupies a significant role in heterocyclic chemistry, with its derivatives drawing increasing interest recently due to their diverse chemistry and pharmacological properties. It is a nitrogen containing heterocyclic ring crucial in both biological processes and pharmaceutical applications. Consequently, imidazole compounds have captivated researchers for over a century, serving as a compelling source of investigation. These derivatives exhibit a wide array of biological activities, including antibacterial, anticancer, anti-tubercular, anti-diabetic activity, anti-fungal, anti-inflammatory activity and anti-HIV effects. This review aims to chronicle the historical evolution of imidazole’s biological activities and the work reported on the synthesis of imidazole derivatives. A multitude of imidazole derivatives are available and the incorporation of the imidazole nucleus remains a pivotal strategy in synthetic drug discovery.
Keywords	Imidazole, Heterocyclic chemistry, Biological activities, Antibacterial, Anticancer, Anti-tubercular, Anti-fungal, Anti-diabetic activity, Anthelmintics activity, Anti-inflammatory activity and Anti-HIV effects.
Field	Chemistry > Pharmacy
Published In	Volume 6, Issue 5, September-October 2024
Published On	2024-10-29
DOI	https://doi.org/10.36948/ijfmr.2024.v06i05.29511

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