The Potential Utilization of Virucidal Nanoparticles as “Nano-traps” in Development of Potential Therapeutics Against the Emerging SARS-CoV-2 Variants

Author(s)	Mirza Niaz Zaman Elin
Country	Bangladesh
Abstract	The rapid spreading of emerging variants and sub-variants such as the delta and omicron variants and the relevant sub-variants of SARS-CoV-2 and associated mortality is truly alarming. Considering the current situation, development of effective countermeasures is an urgent need. Utilization of nano particle based therapeutics can be proven as an effective option which can be developed in shortest possible period of time. When suspended in a preprocessed protein filled solution, metal nano particles such as Silver nanoparticles (AgNPs), Gold nanoparticles (AuNPs) have an innate nature to facilitate attachment of the surrounding protein structures on their surfaces. This phenomenon is known as protein corona formation. The proposal is to utilizing this innate nature of the metal nano particles to synthesize virucidal nano particles which can be used as a medical countermeasure the emerging variants of SARS-CoV-2.
Keywords	Nanoparticles, Metal, Therapeutics, SARS-CoV-2, Coronavirus,Complex, Spike proteins
Field	Medical / Pharmacy
Published In	Volume 5, Issue 3, May-June 2023
Published On	2023-05-31
DOI	https://doi.org/10.36948/ijfmr.2023.v05i03.3340

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International Journal For Multidisciplinary Research