International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 2 (March-April 2025) Submit your research before last 3 days of April to publish your research paper in the issue of March-April.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 7 Issue 2
March-April 2025

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Role of Insect-Derived Antimicrobial Peptides in Overcoming Multidrug-Resistant Infections

Author(s) Dr. Priti Saxena
Country India
Abstract The rise of antibiotic resistance has emerged as a critical global health threat, necessitating the urgent development of novel antimicrobial agents. Insect-derived antimicrobial peptides (AMPs) offer a promising alternative to conventional antibiotics due to their broad-spectrum activity, rapid bactericidal mechanisms, and reduced likelihood of inducing resistance. Insects, which constitute the largest and most diverse group of organisms, have evolved a sophisticated innate immune system that produces AMPs to counteract microbial infections. These peptides exhibit diverse structures and mechanisms of action, including membrane disruption, inhibition of intracellular targets, and modulation of immune responses. Notable insect AMPs, such as defensins, cecropins, and drosocins, have demonstrated potent activity against multidrug-resistant (MDR) bacterial strains, including Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. This review explores the potential of insect-derived AMPs as next-generation therapeutics to combat antibiotic resistance. It examines their structural diversity, mechanisms of action, and efficacy against MDR pathogens. Furthermore, it discusses the challenges associated with their clinical application, including stability, toxicity, and large-scale production, along with recent advancements in synthetic modifications and nanotechnology-based delivery systems. By harnessing the antimicrobial potential of insect AMPs, researchers can develop innovative strategies to address the growing crisis of antibiotic resistance. This study highlights the necessity of integrating insect-derived AMPs into the antibiotic pipeline and emphasizes their role as a viable solution for the post-antibiotic era.
Keywords Insect antimicrobial peptides, antibiotic resistance, multidrug-resistant bacteria, innate immunity, therapeutic peptides, alternative antibiotics, AMPs
Field Biology > Zoology
Published In Volume 7, Issue 2, March-April 2025
Published On 2025-04-18
DOI https://doi.org/10.36948/ijfmr.2025.v07i02.41583
Short DOI https://doi.org/g9f4sm
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 7 Isu 2Cover Page Vol 7 Isu 1Cover Page Vol 6 Isu 6

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com