International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 3 (May-June 2025) Submit your research before last 3 days of June to publish your research paper in the issue of May-June.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 7 Issue 3
May-June 2025

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

NOVEL ORO-DISPERSIBLE FILMS WITH COMBINED MOUTH FRESHENING AND ANTIBACTERIAL PROPERTIES.

Author(s) Mr. Makrand Ekatpure, Mr. Gaurav Yadav, Ms. Iram Naaz Shaikh, Mr. Archit Desai, Ms. Uzma Khan, Mr. Ayush Kate
Country India
Abstract Novel oro-dispersible films with combined mouth freshening and antibacterial properties were developed using liquorice extract as the mouth freshening agent and antibacterial agents to combat bacterial growth. The introduction of these films aims to provide a convenient and effective way to maintain oral hygiene. The objective of this study was to design and evaluate the performance of these novel oro-dispersible films.
Liquorice extract was obtained from the root of the liquorice plant through a process of extraction. The extract was then incorporated into the films along with antibacterial agents. The films were evaluated for their mouth freshening and antibacterial properties using various tests. The Franz diffusion test was used to determine the release of the mouth freshening agent from the films. The integration test was used to evaluate the antibacterial properties of the films. Organoleptic tests were also conducted to assess the taste, odor, and texture of the films. The antibacterial properties of the films were evaluated using Staphylococcus aureus as the test microorganism. The films were also characterized using FTIR spectroscopy to detect the functional groups present. The disintegration of the drug from the films was studied using UV analysis. TLC was used to identify the presence of liquorice extract in the films.The extraction of liquorice from the root was done using a solvent extraction method.The results showed that the novel oro-dispersible films exhibited excellent mouth freshening and antibacterial properties. The films disintegrated quickly in the mouth, releasing the mouth freshening agent and antibacterial agents. The antibacterial properties of the films were effective against Staphylococcus aureus. The FTIR spectra showed the presence of functional groups corresponding to the liquorice extract. The UV analysis showed that the drug disintegrated quickly from the films. The TLC results confirmed the presence of liquorice extract in the films.
Overall, the novel oro-dispersible films with combined mouth freshening and antibacterial properties showed promising results and could be a potential oral hygiene product. The use of liquorice extract as the mouth freshening agent and antibacterial agents to combat bacterial growth makes these films an effective and convenient way to maintain oral hygiene.
Keywords Oro-dispersible films, Buccal films, Mouth freshening, Oral Hygiene ,Antibacterial properties, Novel drug delivery systems, Pharmaceutical applications.
Field Medical / Pharmacy
Published In Volume 7, Issue 2, March-April 2025
Published On 2025-04-26
DOI https://doi.org/10.36948/ijfmr.2025.v07i02.41846
Short DOI https://doi.org/g9gvdp
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 7 Isu 2Cover Page Vol 7 Isu 1Cover Page Vol 6 Isu 6

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com