International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 8, Issue 5 (September-October 2026) Submit your research before last 3 days of October to publish your research paper in the issue of September-October.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 8 Issue 5
September-October 2026

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF PERINDOPRIL ERBUMINE IN BULK DRUG AND DOSAGE FORM BY UV SPECTROSCOPY

Author(s) Ms. Mitali Yuvraj Pawar, Mr. Bhagyashri Sunil Bachhav, Mr. Abhishek Sanjay Shinde, Mr. Prasad Shivaji Shewale, Mr. Shiv Sahebrao More, Ms. Snehal Digambar Bhamare
Country India
Abstract Perindopril, an angiotensin-converting enzyme (ACE) inhibitor, is a vital therapeutic agent in cardiovascular diseases. This study presents a robust method for the development and validation of perindopril bulk by UV spectroscopy. The method was validated following International Conference on Harmonization (ICH) guidelines. The UV method was performed using a UV-Vis spectrophotometer. The optimized conditions involved the use of methanol as the solvent. The calibration curve was found to be linear over the concentration range of X to Y µg/ml with a correlation coefficient (r^2) of Z. The method exhibited good precision with a relative standard deviation (RSD) of less than 2%. The accuracy of the method was confirmed with a recovery study yielding results within the acceptable range. The proposed method was successfully applied for the determination of perindopril bulk in pharmaceutical formulations. The results indicate that the developed UV spectroscopic method is accurate, precise, and sensitive for the estimation of perindopril bulk. Thus, the developed method can be used for routine quality control analysis of perindopril bulk in pharmaceutical industries, ensuring its efficacy and safety.
Keywords International Conference on Harmonization, Angiotensin-Converting Enzyme (ACE), Ultra Violet Spectroscopy, Relative Standard Deviation, PERINDROPIL
Field Medical / Pharmacy
Published In Volume 7, Issue 2, March-April 2025
Published On 2025-04-20
DOI https://doi.org/10.36948/ijfmr.2025.v07i02.42256
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI prefix of IJFMR is 10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com
Powered by Sky Research Publication and Journals