International Journal For Multidisciplinary Research

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Primary mediastinal seminoma: a case report

Author(s) Dr. SARA MOUMNI, Prof. Dr. Hajar Arfaoui, Prof. Dr. Salma Msika, Prof. Dr. Hajar Bamha, Prof. Dr. Nabil Bougteb, Prof. Dr. Wiam El Khattabi, Prof. Dr. Moulay Hicham Afif
Country Morocco
Abstract Primary mediastinal seminoma is a rare and distinct form of malignant germ cell tumor that originates in the mediastinal region. While seminomas are more commonly found in the testes, their mediastinal occurrence accounts for approximately 5% of cases. This type of cancer, typically diagnosed in young adults, is characterized by its generally indolent course, although in some instances, it may present with symptoms related to the compression of adjacent organs or metastasis. The diagnosis is based on histological examination, and chemotherapy is the cornerstone of treatment, offering a generally favorable prognosis with a low risk of recurrence. We report the case of a 25-year-old male, with no history of toxic habits, who was admitted to our institution following the incidental radiological discovery of right mediastinal enlargement. The diagnosis was histologically confirmed via a CT-guided trans-thoracic biopsy, suggesting primary mediastinal seminoma. Therapeutic management consisted of chemotherapy. The patient's clinical course has been favorable, with no signs of recurrence observed to date.
Keywords séminoma, mediastinal, primary, tumor markers
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2025
Published On 2025-05-28
DOI https://doi.org/10.36948/ijfmr.2025.v07i03.42364
Short DOI https://doi.org/g9mh76
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E-ISSN 2582-2160
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