International Journal For Multidisciplinary Research

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Correlation Between Digestive Disorders in Chronic Pancreatitis with Exocrine Insufficiency and Clinical Indicators of Chronic Periodontitis

Author(s) Prof. Dr. Saodat Khamidullaevna Yusupalikhodjaeva, Dr. Khurriyat Olimjon qizi Mukimova, Dr. Gulrukh Bakhtiyor qizi Ishniyazova, Dr. Dildora To’lqin qizi Azimova, Mr. Diyorbek Elbekovich Abdunazarov
Country Uzbekistan
Abstract This study investigates the correlation between digestive disorders in chronic pancreatitis (CP) with exocrine insufficiency and clinical indicators of chronic periodontitis to elucidate their interaction mechanisms. The study included a main group (24 patients) receiving adapted interdisciplinary therapy and a comparison group (22 patients) undergoing standard treatment. Clinical periodontitis indices (OHI-S, SBI, PI, PMA, periodontal pocket depth), coprological parameters, and fecal pH were evaluated. Weak to moderate correlations (r = 0,21–0,57, p < 0,05) were identified between oral hygiene, gingival bleeding, pocket depth, and digestive disorders, with a strong correlation between fecal mucus and leukocytes (r = 0,78). The findings confirm that malabsorption and dysbiosis in CP exacerbate periodontal pathology via systemic inflammation, highlighting the need for an interdisciplinary approach to diagnosis and treatment.
Keywords chronic pancreatitis, chronic periodontitis, digestive disorders, exocrine insufficiency, malabsorption, dysbiosis, clinical indicators, correlation, systemic inflammation.
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2025
Published On 2025-05-21
DOI https://doi.org/10.36948/ijfmr.2025.v07i03.43420
Short DOI https://doi.org/g9mh7x
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