
International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
•
Impact Factor: 9.24
A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal
Home
Research Paper
Submit Research Paper
Publication Guidelines
Publication Charges
Upload Documents
Track Status / Pay Fees / Download Publication Certi.
Editors & Reviewers
View All
Join as a Reviewer
Get Membership Certificate
Current Issue
Publication Archive
Conference
Publishing Conf. with IJFMR
Upcoming Conference(s) ↓
WSMCDD-2025
GSMCDD-2025
Conferences Published ↓
ICCE (2025)
RBS:RH-COVID-19 (2023)
ICMRS'23
PIPRDA-2023
Contact Us
Plagiarism is checked by the leading plagiarism checker
Call for Paper
Volume 7 Issue 3
May-June 2025
Indexing Partners



















ANTIFUNGAL ACTIVITIES OF Moringa oleifera ETHANOLIC LEAF EXTRACT AGAINST Aspergillus niger
Author(s) | Ms. Regina Marie Muyco Tuquib, Dr. Jamilah Baragona |
---|---|
Country | Philippines |
Abstract | Aspergillus niger is a filamentous fungus commonly found in soil, decaying organic matter, and indoor environments. While it is widely used in various industrial applications, it is also an opportunistic pathogen capable of causing severe infections, particularly in immunocompromised individuals. The increasing resistance of fungi to conventional antifungal treatments has underscored the need for alternative remedies. Moringa oleifera is known for its medicinal properties and has demonstrated antimicrobial effects against a range of pathogens. In this study, fresh Moringa oleifera leaves were collected, authenticated, and processed for ethanolic extraction at the University of the Philippines–Los Baños (UPLB) Chemistry Institute. The extract was subsequently tested against A. niger at BIOTECH-UPLB, using varying concentrations (25%, 50%, 75%, and 100%). The fungal isolate, Aspergillus niger (accession number BIOTECH 3225), was obtained from the Philippine National Collection of Microorganisms (PNCM), a recognized repository for microbial strains in the Philippines. Itraconazole was used as the positive control. A t-test was conducted to compare the antifungal effects of the 100% Moringa oleifera ethanolic leaf extract and Itraconazole against A. niger. The results showed that the Moringa extract produced no inhibition zones (0 mm), while Itraconazole demonstrated significant inhibition (13.86 mm and 12.38 mm). The t-test revealed a statistically significant difference (p = 0.000), indicating that Itraconazole is significantly more effective than the Moringa extract in inhibiting A. niger growth. These findings suggest that the ethanolic leaf extract of Moringa oleifera lacks antifungal activity against A. niger under the tested conditions. However, further research is warranted—exploring different plant parts, extraction methods, or fungal targets—to fully assess the broader antimicrobial potential of M. oleifera. |
Keywords | Aspergillus niger, Moringa oleifera, ethanolic leaf extract, Itraconazole, antifungal effects, antimicrobial |
Field | Medical / Pharmacy |
Published In | Volume 7, Issue 3, May-June 2025 |
Published On | 2025-05-09 |
Share this

E-ISSN 2582-2160

CrossRef DOI is assigned to each research paper published in our journal.
IJFMR DOI prefix is
10.36948/ijfmr
Downloads
All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.
