International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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Volume 7 Issue 3
May-June 2025

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Formulation and Evaluation Combination of Anti-inflammation and Skeletal muscle relaxant gel.

Author(s) Ms. Shraddha Haridas Mahabole, Dr. Balakrishna Tiwari, Ms. Mahevish Samir Ahmad Hudewale, Ms. Neha Bhimrao Harihar, Ms. Vaishnavi Ramchandra Hatture
Country India
Abstract This study focuses on developing a topical gel formulation that combines a nonsteroidal anti-inflammatory drug (NSAID) and a muscle relaxant to manage musculoskeletal pain and inflammation. The gel's physicochemical properties, including spreadability, pH, and viscosity, were evaluated to ensure optimal performance. The solution showed good spreadability, an ideal viscosity for user-friendliness, and a pH appropriate for skin application. In investigations on skin irritation, there were few negative reactions, suggesting acceptable tolerance. A topical gel containing NSAID and muscle relaxant offers a promising treatment option for musculoskeletal disorders by reducing systemic adverse effects and reducing localised pain. There may be clinical uses for this formulation in the treatment of ailments like sports injuries, muscle spasms, and lower back discomfort. The created gel composition offers patients with musculoskeletal pain and inflammation a practical and efficient therapeutic choice. Systemic exposure and any adverse effects are reduced by the gel's direct delivery of the active components to the site of action. The clinical efficacy and safety of this formulation need to be investigated further.
Keywords Anti-inflammatory , Muscle relaxant properties, Topical gel formulation, Evaluation parameters
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2025
Published On 2025-05-20
DOI https://doi.org/10.36948/ijfmr.2025.v07i03.45217
Short DOI https://doi.org/g9kvfk
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