International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 3 (May-June 2025) Submit your research before last 3 days of June to publish your research paper in the issue of May-June.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 7 Issue 3
May-June 2025

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Ventilator-associated pneumonia

Author(s) Dr. Amine Schahrakane, Dr. Soufiane Hansal, Prof. Dr. Anas Mounir, Prof. Dr. Rachid charqab, Prof. Dr. chafik el hamidi el kettani
Country Morocco
Abstract Ventilator-associated pneumonia (VAP) is defined as a pulmonary infection acquired after at least 48 hours of assisted ventilation. They represent the most frequent healthcare-associated infectious complication (30-50%). The diagnostic, therapeutic and preventive quality of their management represents a major challenge for intensive care physicians, as well as an important economic issue.
The aim of our work is to determine the epidemiological, clinical, therapeutic and prognostic aspects of healthcare-associated pneumonia, as well as to study the microbiological profile of these types of infection in our department.
This is a retrospective study carried out in the P17 surgical resuscitation department of CHU Ibn Rochd in Casablanca over a 2-year period from January 1, 2023 to December 31, 2024. We collected 510 lung samples including 1 BAL, 19 ASP, 486 PBDP and 3 sputum from patients hospitalized in this department. We included in our study patients hospitalized in the P17 surgical intensive care unit, who had taken lung samples and received mechanical ventilation.
Among the 1,770 intubated and ventilated patients admitted to the intensive care unit during the period of our study, 238 patients had care-associated pneumonia, an incidence equal to 13.44%.
The mean age of the patients was 57.04 years, with extremes ranging from 16 to 67 years. There was a clear male predominance: 67% of patients were male.
In all patients, the most frequent reason for hospitalization was post-operative management.
In our study, the use of antibiotics prior to resuscitation was noted in 40 patients (16.81%). Amoxicillin-clavulanic acid was the most commonly used antibiotic.
Purulent secretions were observed in 114 patients (47.9%). A very high CRP level (over 100 mg/l) was found in 52% of our patients. 42% of these patients showed hyperleukocytosis, 12% leukopenia and 35% thrombocytopenia.
On all selected samples, 6 main bacteria were found; Acinetobacter baumannii was the most frequent representing 28% of all germs, followed by Pseudomonas aeruginosa 14%, Klebsiella pneumoniae ssp pneumoniae 13%, Staphylococcus aureus 8%, Escherichia coli 6%, then coagulase-negative Staphylococcus 5%. In our study, of the 238 positive cultures, we found 29 polymicrobial cultures versus 209 monomicrobial cultures.
In our series, 209 patients (87.8%) were treated with antibiotics. Overall, the mean duration of antibiotic treatment was approximately 12.9 days. Poly-antibiotic therapy was the usual mode of treatment, accounting for 85% of cases (179 patients). Imipenem, amikacin and colistin were the ATB combinations most commonly used in these patients.
Progress was assessed clinically (temperature, hemodynamic and respiratory status, state of consciousness, etc.), biologically (CBC, blood gas, CRP, renal function, etc.) and bacteriologically. The average length of hospital stay for patients with healthcare-associated pneumonia was 22 days, with extremes ranging from 1 to 102 days. This outcome was favorable in only 47 of our patients (19.75%), while 191 of our patients (80.25%) died.
Keywords Ventilator-associated pneumonia (VAP) ; pulmonary infection ; microbiological profile ; epidemiological ; resuscitation
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2025
Published On 2025-05-31
DOI https://doi.org/10.36948/ijfmr.2025.v07i03.45568
Short DOI https://doi.org/g9m28k
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 7 Isu 3Cover Page Vol 7 Isu 2Cover Page Vol 7 Isu 1

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com