International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 3 (May-June 2025) Submit your research before last 3 days of June to publish your research paper in the issue of May-June.

A REVIEW ON STROKE: RISK FACTORS,PREVENTION, AND EMERGING RESEARCH

Author(s) Miss Pragati Shivaji Panchal, Miss Shivani Arun Bhange, Mr. Amit Hanmant Bhadarge, Dr. Ajay Fugate
Country India
Abstract Stroke remains a significant global health concern, ranking as one of the leading causes of mortality and long-term disability worldwide. This review explores the multifaceted aspects of stroke, encompassing its risk factors, prevention strategies, and recent advancements in research aimed at improving outcomes and reducing incidence rates. Stroke is broadly categorized into ischemic and hemorrhagic subtypes, each with distinct etiologies and clinical presentations. The identification and management of risk factors such as hypertension, diabetes mellitus, dyslipidemia, smoking, atrial fibrillation, and sedentary lifestyle play a pivotal role in primary and secondary prevention.
Hypertension emerges as the most influential modifiable risk factor, contributing to both ischemic and hemorrhagic strokes. Smoking and excessive alcohol consumption exacerbate vascular damage and elevate stroke risk, while physical inactivity and obesity create a predisposition to metabolic syndromes that potentiate cerebrovascular events. Advances in imaging and diagnostic modalities have enhanced the precision of early stroke detection, aiding in timely interventions. This review underscores the importance of public health initiatives, including lifestyle modifications and community-based screening programs, in mitigating the stroke burden.
Pharmacological interventions, particularly antiplatelet therapy, anticoagulation for atrial fibrillation, and lipid-lowering agents, have shown efficacy in reducing stroke incidence. Furthermore, thrombolysis with tissue plasminogen activator (tPA) and endovascular thrombectomy have revolutionized acute stroke management, improving survival rates and functional outcomes. Emerging research highlights the role of genetic predispositions, inflammatory pathways, and novel biomarkers in stroke risk stratification and prognosis. The advent of telemedicine and artificial intelligence (AI) in stroke care has also demonstrated potential in optimizing resource allocation and delivering personalized treatment.
Recent studies emphasize the need for integrated care models that encompass neurorehabilitation, mental health support, and long-term monitoring for stroke survivors. Innovative therapies, including neuroprotective agents and stem cell transplantation, are being explored, although their clinical applicability remains under investigation. Additionally, disparities in stroke care across different socioeconomic strata necessitate policy reforms and equitable access to healthcare services.
In conclusion, the fight against stroke requires a multidisciplinary approach that bridges gaps in prevention, diagnosis, treatment, and rehabilitation. While strides have been made in understanding the pathophysiology and management of stroke, ongoing research is imperative to address unresolved challenges and enhance quality of life for those affected. This review serves to consolidate current knowledge, advocate for evidence-based practices, and inspire further investigations in the realm of stroke research.
Keywords Stroke, risk factors, lifestyle changes, genetic risk factors , nonmodifiable risk factors , and modifiable risk factors .
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2025
Published On 2025-05-31
DOI https://doi.org/10.36948/ijfmr.2025.v07i03.45647
Short DOI https://doi.org/g9mtrx

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