International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Volume 7 Issue 3
May-June 2025

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A Comprehensive Review Nanosponges as Novel carries in Antifungal Therapy

Author(s) Mr. Onkar Vilas Kanawade, Mr. Aditya Mukundrao Dahiphale, Mr. Akshay Sitaram Chavhan, Mr. Harshad Ganeh Kangude, Mr. Sham Bhagwan Gitte, Mr. Shreyash k Pardeshi
Country India
Abstract The recent advance in nanotechnology has led to the development of targeted drug delivery system. However, targeting a molecule to a particular Site using a drug delivery system effectively requires a specialized drug delivery system. The discovery of Nano sponge has become a significant step in overcoming certain problems such as drug toxicity, poor bioavailability and release of drug in a predictable fashion as they can accommodate both hydrophilic and hydrophobic drug. Nanosponges are minute, sponge-like carriers characterized by their porous architecture, which enables them to encapsulate active drug molecules efficiently. Their distinctive structure allows for a controlled and sustained release of therapeutic agents. These nanoscale systems can circulate throughout the body, navigate to the targeted site, adhere to the surface, and gradually dispense the drug in a regulated and site-specific manner. Nano sponges can be formulated by crosslinking of cyclohexatriene with carbonyl or decarboxylase (Cross linkers). Nanosponges have been widely studied for delivering medicines through different routes, including by mouth (oral), on the skin (topical), and by injection (parenteral).Nano sponges can also serve as an effective carrier for enzyme, proteins, vaccine and antibodies. The Present review highlights the method of preparation, characterization and their potential application in drug delivery system.
Keywords Targeted drug delivery system, Nanosponges, Hydrophilic and Hydrophobic drug
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2025
Published On 2025-06-10
DOI https://doi.org/10.36948/ijfmr.2025.v07i03.47469
Short DOI https://doi.org/g9pz2d
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