An Observational Study on Prescribing Pattern of Drugs and its Outcomes in Renal-Impaired Patients at Tertiary Care Hospital

divya yadav; Dr. Aziz Ahmed; Bhartendra Singh; Divya Yadav

doi:10.36948/ijfmr.2025.v07i03.47842

An Observational Study on Prescribing Pattern of Drugs and its Outcomes in Renal-Impaired Patients at Tertiary Care Hospital

Author(s)	Ms. divya yadav, Dr. Aziz Ahmed, Bhartendra Singh, Divya Yadav
Country	India
Abstract	Renal impairment is characterized by a progressive decline in glomerular filtration rate, a significant public health issue worldwide associated with high morbidity and mortality. In most cases, renal impairment is associated with comorbidities such as hypertension and diabetes, which require multiple drug therapy during a course of treatment, leading to polypharmacy. The objective of this study was to assess the prescribing pattern of drugs in renal impaired patients at Hospital.A total of 150 patients with renal impairment were finally recruited after strictly obeying the selection criteria in this cross sectional, observational study conducted over 6 months in a tertiary care hospital. Relevant data were extracted by interviewing the patients and from prescriptions, case records, and investigational reports. Of the total 150 patients, 94 (63%) were male and 56 (37%) female. The highest numbers of patients were in the age group >60 years (59 patients, 39.3%). Anemia was the most common comorbidity (143 patients, 95%) observed, followed by hypertension (129 patients, 86%) and diabetes mellitus (64 patients, 43%). A total of 1693 drugs were prescribed to 150 renal impaired patients. Each patient received an average of 11.19 ± 3.51 (8%) drugs. Polypharmacy was seen in all patients. Drugs acting on the cardiovascular system constituted the bulk of the prescriptions (25.87%), followed by gastrointestinal (GI) drugs (18.72%), vitamins and minerals (14.94%), and antibiotics (8.33%). There is polypharmacy in patients with renal impairment due to associated comorbidities. The prevalence of polypharmacy was high in patients with kidney disease (KD). Antihypertensive drugs, drugs used for the GI system, antibiotics, and antidiabetic drugs were frequently used in KD patients.
Keywords	Kidney failure, drug utilization, polypharmacy, Prescription pattern, renal impaired
Field	Medical / Pharmacy
Published In	Volume 7, Issue 3, May-June 2025
Published On	2025-06-14
DOI	https://doi.org/10.36948/ijfmr.2025.v07i03.47842
Short DOI	https://doi.org/g9qp87

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An Observational Study on Prescribing Pattern of Drugs and its Outcomes in Renal-Impaired Patients at Tertiary Care Hospital

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