International Journal For Multidisciplinary Research

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Ziziphus jujuba Mill.: A Comprehensive Review of its Phytochemistry and Pharmacological Potential

Author(s) Ms. MUKTA NIVRUTTI GOCHADE, Dr. AMOL CHANDEKAR, Dr. ATUL TRIPATHI
Country India
Abstract Ziziphus jujuba Mill., commonly known as jujube or Chinese date, is a medicinally important plant belonging to the family Rhamnaceae. Widely cultivated across Asia, the Middle East, and parts of Europe, this plant has long been used in traditional medicine systems such as Ayurveda, Traditional Chinese Medicine, and Unani. Various parts of the plant including fruits, leaves, seeds, bark, and roots possess a rich array of phytoconstituents such as flavonoids, saponins, triterpenoids, polysaccharides, phenolic acids, and alkaloids, which contribute to its broad pharmacological profile.
This review provides a comprehensive evaluation of the Pharmacognostic features, phytochemistry, traditional applications, and scientifically validated pharmacological activities of Z. jujuba. The plant exhibits antioxidant, anti-inflammatory, hepatoprotective, neuroprotective, anxiolytic, hypoglycaemic, immunomodulatory, wound healing, and antimicrobial effects across various experimental models. Its therapeutic potential has also been demonstrated in disorders related to the nervous system, metabolic syndrome, and liver dysfunction. The bioactivity is largely mediated through modulation of oxidative stress, neurotransmitter balance, inflammatory pathways, and immune responses.
Despite its promising pharmacological actions, further clinical trials, toxicological evaluations, and standardization of active constituents are essential to validate its safety and efficacy in modern medicine. Ziziphus jujuba stands as a valuable candidate for future phytopharmaceutical development, bridging traditional knowledge with contemporary therapeutic approaches.
Keywords Ziziphus jujuba, jujube, phytochemistry, pharmacological activity, traditional medicine, phytopharmacology
Field Medical / Pharmacy
Published In Volume 7, Issue 3, May-June 2025
Published On 2025-06-25
DOI https://doi.org/10.36948/ijfmr.2025.v07i03.49221
Short DOI https://doi.org/g9rskd
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