Review on  Rapid Enantiomeric Analysis of Chiral Carboxylic Acids Using Visible CD Signatures

Author(s)	Ms. ANKITA SHARMA, Ms. MANPREET KAUR, Ms. SUKHPREET KAUR
Country	India
Abstract	In order to create a metal complex that is chiroptically active and exhibits strong circular dichroism (CD) responses in the visible spectrum—a crucial objective in optical sensing research—a chiral carboxylic acid reacts with 1,1′-bis(diphenylphosphino) ferrocene palladium dichloride when exposed to a mild base. Within minutes, this technique allows for the quick chiroptical measurement of carboxylic acid sample concentration and enantiomeric purity. The method is simple and adaptable, and it can be used with a wide variety of chemical substances, such as natural chemicals, medicines, hydroxy acids, and amino acids. Furthermore, because all necessary reagents are widely available, the assay is very accessible and may be easily included into any lab that focuses on chirality or high-throughput screening.
Keywords	Chirality, Building block, Enantiomers and CD Effects
Field	Chemistry > Pharmacy
Published In	Volume 7, Issue 3, May-June 2025
Published On	2025-06-25
DOI	https://doi.org/10.36948/ijfmr.2025.v07i03.49264
Short DOI	https://doi.org/g9rj3h

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