A Case Report on Amisulpride-Induced Hyperprolactinemia Presenting as Secondary Amenorrhea

Author(s)	Dr. Ancy Anil, Dr. RINTO JOSE PRATHEEKSH, Prof. Dr. ANULEKHA MARY JOHN
Country	India
Abstract	Amisulpride, an atypical antipsychotic, a selective dopamine D2/ D3 receptor antagonist, is commonly used for treating psychosis and mood disorders. However, one of its known adverse effects is hyperprolactinemia due to dopamine blockade in the tuberoinfundibular pathway. We report the case of a 41-year-old woman who developed secondary amenorrhea following initiation of amisulpride. Her investigations showed a marked increase in prolactin level. Her symptoms improved after discontinuing amisulpride. This case highlights the importance of recognizing medication-induced endocrine dysfunction.
Keywords	Hyperprolactinemia, Amisulpride, Amenorrhea, Prolactin.
Field	Medical / Pharmacy
Published In	Volume 7, Issue 3, May-June 2025
Published On	2025-06-25
DOI	https://doi.org/10.36948/ijfmr.2025.v07i03.49340
Short DOI	https://doi.org/g9rj2x

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