Evaluation toxicity in ethanolic extract of Capparis sepiaria L. Leaf.

Author(s)	Dr. Manjula A Rathod, PRATIMA MATHAD, SHIVKUMAR INAMDAR, NITIN MAHURKAR
Country	India
Abstract	India is known for its rich tradition in human wealth and medicine from decades. It is also home for many valuable medicinal plants which are being used in the different system of medicines. Capparis sepiaria known as himsra in Ayurveda, is used as an active ingredient in many oils. The present study aimed to evaluate acute oral toxicity studies in the ethanolic extract of Capparis sepiaria leaf. The acute oral toxicity was carried out as per OECD guidelines and as Sabbani et. al. 2015). Results: The acute oral toxicity of ethanolic extract of Capparis sepiaria leaf was found non-toxic at 175, 250, 500, and 1000mg/kg whereas LD50 was found at 2000mg/kg. The present study concluded that the ethanolic extract of Capparis sepiaria leaf was non-toxic at the studied dose which can have important pharmacological actions in future herbal preparations.
Keywords	Acute oral toxicity. Capparis sepiaria, ethanolic extract, leaf and Wister albino rats.
Field	Biology > Medical / Physiology
Published In	Volume 7, Issue 3, May-June 2025
Published On	2025-06-30
DOI	https://doi.org/10.36948/ijfmr.2025.v07i03.49950
Short DOI	https://doi.org/g9r8cq

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