International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Volume 7 Issue 4
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Unlocking the Therapeutic Potential of Catharanthus roseus: A Modern Pharmacological Perspective on a Historic Medicinal Plant

Author(s) Dr. Dolly Chakraborty, Mr. Lokokrishna Jha
Country India
Abstract Catharanthus roseus (family: Apocynaceae) is a widely distributed medicinal plant that holds a prominent
place in various traditional healthcare systems across the globe. Over the past few decades, scientific
inquiry has increasingly substantiated many of its historical uses, unveiling a spectrum of
pharmacological activities that align with its ethnomedicinal legacy. Notably, contemporary research has
confirmed its therapeutic potential in managing cancer, diabetes, neurodegenerative disorders, and
microbial infections. This review offers a comprehensive examination of the plant’s bioactive profile,
focusing on its major phytochemical constituents and their associated pharmacodynamics. Special
emphasis is placed on indole alkaloids such as vinblastine and vincristine, which have revolutionized
cancer chemotherapy, as well as compounds like vinpocetine, a semisynthetic derivative with promising
neuroprotective properties. Drawing upon 30 high-impact, peer-reviewed sources, this article bridges the
gap between traditional botanical wisdom and modern biomedical science. By integrating
pharmacognostic data with current clinical insights, this work aims to highlight the multifaceted
therapeutic potential of C. roseus while identifying emerging opportunities for drug development and
translational research.
Keywords Catharanthus roseus, vincristine, alkaloids, antidiabetic, anticancer, neuroprotective, phytotherapy
Field Chemistry
Published In Volume 7, Issue 4, July-August 2025
Published On 2025-07-05
DOI https://doi.org/10.36948/ijfmr.2025.v07i04.50018
Short DOI https://doi.org/g9s9bm
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