
International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
•
Impact Factor: 9.24
A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal
Home
Research Paper
Submit Research Paper
Publication Guidelines
Publication Charges
Upload Documents
Track Status / Pay Fees / Download Publication Certi.
Editors & Reviewers
View All
Join as a Reviewer
Get Membership Certificate
Current Issue
Publication Archive
Conference
Publishing Conf. with IJFMR
Upcoming Conference(s) ↓
WSMCDD-2025
GSMCDD-2025
AIMAR-2025
Conferences Published ↓
ICCE (2025)
RBS:RH-COVID-19 (2023)
ICMRS'23
PIPRDA-2023
Contact Us
Plagiarism is checked by the leading plagiarism checker
Call for Paper
Volume 7 Issue 4
July-August 2025
Indexing Partners



















Phytochemical Profiling of MARMAGULIKA LEPAM Using GC-MS Analysis: Identification of Volatile and Bioactive Compounds
Author(s) | Dr. Sreedevi A P, Reeshma CR, Anju Antony, Sibi Narayana |
---|---|
Country | India |
Abstract | Introduction: Marmagulika Lepam (MG Lepam), a polyherbal Ayurvedic formulation from Sahasrayogam, is used topically for its anti-inflammatory and analgesic properties in treating dermatological and musculoskeletal disorders. Unlike synthetic drugs, MG Lepam offers a natural alternative with minimal side effects, leveraging a diverse mix of herbal ingredients. Materials and Methods: Raw materials were sourced and MG Lepam was prepared per classical Ayurvedic protocols, triturating powdered herbs with decoctions to form a homogeneous paste. Organoleptic, physicochemical, phytochemical, Heavy metal Analysis and GC-MS analyses were conducted to assess the formulation’s properties and safety.Results and Discussion: MG Lepam exhibited a dark brown color, characteristic odor, and smooth consistency. Its pH (4.98) aligns with skin compatibility, with 53.1% moisture and 5981 cP viscosity ensuring stability and spreadability. Phytochemical analysis confirmed carbohydrates, sugars, proteins, glycosides, phenols, saponins, and quinones, supporting its therapeutic effects. HMT showed negligible heavy metal levels. GC-MS identified bioactive compounds like palmitic (12.279%), oleic (16.454%), and linoleic (12.542%) acid methyl esters, contributing anti-inflammatory, antioxidant, and antimicrobial properties, with cyclohexanol (25.543%) enhancing transdermal absorption.Conclusion: MG Lepam is a safe, effective topical Ayurvedic formulation, validated by comprehensive analyses. Its skin-compatible properties and bioactive compounds support its use for pain and inflammation management, offering a natural alternative to synthetic analgesics and a model for standardizing Ayurvedic formulations for global healthcare integration. |
Keywords | Marmagulika Lepam, Anti-inflammatory, GC-MS Analysis, Phytochemicals, Heavy Metal Toxicity, Topical Application |
Published In | Volume 7, Issue 4, July-August 2025 |
Published On | 2025-07-30 |
DOI | https://doi.org/10.36948/ijfmr.2025.v07i04.50025 |
Short DOI | https://doi.org/g9vphm |
Share this

E-ISSN 2582-2160

CrossRef DOI is assigned to each research paper published in our journal.
IJFMR DOI prefix is
10.36948/ijfmr
Downloads
All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.
