Effectiveness of the Modified NUTRIC Score in Predicting Mortality Among Mechanically Ventilated Critically Ill Patients in a North Indian Tertiary Care ICU

Soumya Ranjan Mohanty; Mallavarapu Manisha; Manish Kumar

doi:10.36948/ijfmr.2025.v07i04.50106

Effectiveness of the Modified NUTRIC Score in Predicting Mortality Among Mechanically Ventilated Critically Ill Patients in a North Indian Tertiary Care ICU

Author(s)	Dr. Soumya Ranjan Mohanty, Dr. Mallavarapu Manisha, Dr. Manish Kumar
Country	India
Abstract	Background: The modified Nutrition Risk in Critically Ill (m-NUTRIC) score is a validated tool for predicting mortality and clinical outcomes in critically ill patients globally. This study aims to evaluate the effectiveness of the m-NUTRIC score in predicting mortality among mechanically ventilated patients in a tertiary care ICU in North India. Methodology: A cross-sectional observational study was conducted in the medical ICU of a tertiary care hospital in North India. Baseline clinical, hematological, and biochemical parameters, mNUTRIC, APACHE II and SOFA scores were collected within 24 hours of ICU admission, and patients were followed for ICU length of stay and 28-day mortality. Statistical analysis included ROC curve assessment and evaluation of sensitivity and specificity for mNUTRIC, APACHE II, and SOFA scores in predicting mortality. Results: Among 114 mechanically ventilated ICU patients, hypertension (31.6%) and diabetes (23.7%) were the most common comorbidities. High nutritional risk (mNUTRIC ≥5) was present in 35.1% of patients. The mNUTRIC score showed a sensitivity of 70%, specificity of 68.9%, PPV of 54.9%, and NPV of 81% for predicting mortality. APACHE II had higher sensitivity (80%) and specificity (74.3%), with a PPV of 62.7% and NPV of 87.3%. SOFA demonstrated the highest sensitivity (83.9%), specificity of 69.9%, PPV of 51.0%, and NPV of 92.1%. However, ROC analysis revealed only modest discriminatory power for all three scores: mNUTRIC (AUC 0.5915), APACHE II (AUC 0.5842), and SOFA (AUC 0.5223). Conclusion: The mNUTRIC score is a practical tool for predicting mortality in ICU patients, but larger multi-center studies are needed to validate its effectiveness across diverse populations.
Keywords	mNUTRIC, ICU, APACHE 2, SOFA
Field	Medical / Pharmacy
Published In	Volume 7, Issue 4, July-August 2025
Published On	2025-07-03
DOI	https://doi.org/10.36948/ijfmr.2025.v07i04.50106
Short DOI	https://doi.org/g9r7nm

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Effectiveness of the Modified NUTRIC Score in Predicting Mortality Among Mechanically Ventilated Critically Ill Patients in a North Indian Tertiary Care ICU

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