International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Guarding the Line: A Systematic Review of Nurse-Led Infection Prevention Protocols for Reducing Catheter-Related Bloodstream Infections in Hemodialysis Settings

Author(s) Christine Lourdes Tan Evalaroza, Sarah Bernadette Lozada Baleña
Country Philippines
Abstract Background: Catheter-related bloodstream Infections (CRBSIs) are a significant cause of morbidity and mortality among patients undergoing hemodialysis via central venous catheters (CVCs). As frontline caregivers, nurses are uniquely positioned to lead infection prevention efforts. This systematic review aimed to evaluate the effectiveness of nurse-led infection prevention protocols in reducing CRBSIs in hemodialysis settings.

Methods: A comprehensive literature search was conducted across ScienceDirect, Google Scholar, ProQuest, and EBSCO, yielding 572 studies. Following title and abstract screening, full-text review, and critical appraisal using the CONSORT checklist, eight studies met the inclusion criteria. These studies included randomized controlled trials, quality improvement projects, and cohort designs published between 2013 and 2024. Data were synthesized using a narrative and thematic approach, with analysis structured around the Health Promotion Model (HPM) and the Donabedian Model of Quality of Care.

Results: Three major themes emerged: (1) structured protocol and care bundles, (2) quality improvement and cyclical strategies, and (3) behavior-focused educational interventions. Most studies reported significant reductions in CRBSI rates following the implementation of nurse-led protocols. Interventions that were standardized, well-monitored, and behaviorally reinforced proved most effective. Theoretical integration highlighted how successful interventions relied on individual behavioral change and systemic support structures.

Conclusion: Nurse-led infection prevention protocols are effective strategies for reducing CRBSIs in hemodialysis settings. Their success is amplified when guided by evidence-based practices, structured implementation, continuous quality improvement, and education. The dual application of the HPM and Donabedian Model underscores the need to align behavior change with supportive systems to enhance patient safety and healthcare quality.
Keywords Catheter-related Bloodstream Infections, CRBSI, Hemodialysis, Nurse-led Interventions, Infection Prevention, Quality Improvement, Health Promotion Model, Donabedian Model
Field Medical / Pharmacy
Published In Volume 7, Issue 4, July-August 2025
Published On 2025-07-05
DOI https://doi.org/10.36948/ijfmr.2025.v07i04.50250
Short DOI https://doi.org/g9s9hm
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E-ISSN 2582-2160
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