International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 4 (July-August 2025) Submit your research before last 3 days of August to publish your research paper in the issue of July-August.

Therapeutic & Diagnostic Applications of Biosurfactants of Microbial Origin

Author(s) Dr. Mukesh Chander, Dr. Maman Paul
Country India
Abstract Biosurfactants, amphipathic molecules predominantly produced by microorganisms, represent a sustainable and versatile alternative to conventional synthetic surfactants. Their unique physicochemical properties, including exceptional surface and interfacial tension reduction, emulsification, and foam stabilisation capabilities, are complemented by significant environmental advantages such as low toxicity, high biodegradability, and production from renewable resources. This review highlights microbial biosurfactant production, detailing key producers, their biosynthesis pathways, and advancements in fermentation and genetic engineering strategies for enhancing yields and altering molecular structures. Furthermore, it examines the critical downstream processing methods for biosurfactant isolation and purification, highlighting both their efficacy and inherent challenges. A significant focus is placed on the diverse and expanding medical and health applications of biosurfactants, particularly their potent antimicrobial and anti-biofilm activities, and innovative roles in drug delivery systems, and their promising immunomodulatory, diagnostic, and therapeutic potentials. While the high production and purification costs currently impede widespread commercialisation, ongoing advancements in biotechnology and process optimisation underscore a future where biosurfactants play an increasingly indispensable role in sustainable healthcare solutions.
Keywords Amphipathic molecules, Biosurfactants, Emulsions, Microbial production, Medical applications
Field Biology > Medical / Physiology
Published In Volume 7, Issue 4, July-August 2025
Published On 2025-07-05
DOI https://doi.org/10.36948/ijfmr.2025.v07i04.50288
Short DOI https://doi.org/g9s9g3

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