International Journal For Multidisciplinary Research

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Non Surgical periapical healing with PRF

Author(s) Dr. Veena Veena, Dr. Vishal Sharma, Dr. Sanjeev Chauhan, Dr. Sonam Yadav
Country India
Abstract Platelet-rich fibrin (PRF) is an autologous blood concentrate obtained without anticoagulants by centrifugation of patients’ peripheral venous blood. PRF is considered to enhance the formation of new bone.
The aim was to present a case reports of permanent teeth with closed apexes with periapical lesions, which was treated endodontically with the use of PRF. The root canals were mechanically cleaned and shaped with NiTi files and irrigated with sodium hypochlorite (NaOCl). Before the canal systems were obturated, PRF was used as a scaffold and was placed below the cementodentinal junction with hand pluggers. Cone beam computerized tomography (CBCT) was used to assess the resolutions of periapical radiolucency’s. After 12 months, the measurements of both periapical lesions were significantly reduced. Although the performed root canal treatments (RCTs) can definitely be recognized as successful, it must be emphasized that mechanical shaping and cleaning of the root canals with special disinfecting solutions significantly affect the clinical efficacy of RCT.
Conclusion: It seems impossible to state that PRF played a leading role in the healing process of the presented periapical lesions. Further studies must be performed to assess whether RCT of mature teeth with an additional PRF application is superior to RCT performed alone.
Keywords PRF,Non surgical healing,periapical lesion
Field Medical / Pharmacy
Published In Volume 7, Issue 4, July-August 2025
Published On 2025-07-17
DOI https://doi.org/10.36948/ijfmr.2025.v07i04.51350
Short DOI https://doi.org/g9tz9d
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