Advanced Neuroimaging Approaches to Pediatric Brain Tumors (2025)

Bharat Bhushan Dagur; Rukamanee yadav

doi:10.36948/ijfmr.2025.v07i04.52258

Advanced Neuroimaging Approaches to Pediatric Brain Tumors (2025)

Author(s)	Mr. Bharat Bhushan Dagur, Ms. Rukamanee yadav
Country	India
Abstract	Introduction: Podiatric brain tumours, especially in the posterior fossa, are a major neuro oncological concern. Medulloblastoma is a common and aggressive tumour requiring accurate imaging for diagnosis and treatment planning. While standard MRI offers anatomical detail, advanced modalities provide critical functional and metabolic information. Aim: To review advanced MRI techniques for evaluating paediatric brain tumours, especially medulla blastula, and their role in diagnosis, grading, and surgical planning. Objectives: Summarize DWI/DTI findings and their significance in tumor cellularity and tract involvement. Explain SWI’s role in detecting haemorrhages and calcifications. Describe MRS metabolite patterns typical of paediatric tumours. Discuss perfusion MRI (DSC, ASL) in evaluating tumour vascularity. Highlight how multimodal imaging supports differential diagnosis and resection strategies. Present tumour-type distribution and key quantitative imaging biomarkers. Methods and Materials: A narrative review of studies (2020–2025) from PubMed, PMC, and Google Scholar focusing on paediatric brain tumours and imaging modalities (DWI/DTI, SWI, MRS, DSC/ASL). Data were extracted and synthesized without new patient involvement. Results: DWI/DTI: Medulloblastomas show low ADC; DTI maps critical fibre tracts. SWI: Detects tumour haemorrhages/calcifications; high ITSS score suggests high grade. MRS: High Cho/NAA and Cho/Cr ratios with lactate peaks in high-grade tumours. Perfusion MRI: Elevated rCBV/CBF in high-grade tumours; ASL offers non-contrast alternative. Multimodal Imaging: Combining methods improves diagnosis and surgical safety. Conclusion: Advanced MRI modalities (DWI, DTI, SWI, MRS, perfusion) significantly enhance paediatric brain tumour evaluation. These methods complement standard MRI, guiding diagnosis, grading, and resection. Adoption of multi-parametric imaging can improve surgical outcomes and potentially allow virtual biopsies.
Keywords	Keywords: Podiatric brain tumour, Medulloblastoma, DWI, Perfusion MRI, Neuroimaging, Surgical planning, MRI biomarkers
Published In	Volume 7, Issue 4, July-August 2025
Published On	2025-07-27
DOI	https://doi.org/10.36948/ijfmr.2025.v07i04.52258
Short DOI	https://doi.org/g9vprk

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Advanced Neuroimaging Approaches to Pediatric Brain Tumors (2025)

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