International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 4 (July-August 2025) Submit your research before last 3 days of August to publish your research paper in the issue of July-August.
Submit Research Paper Join as a Reviewer

Plagiarism is checked by the leading plagiarism checker TurnItIn

Call for Paper

Volume 7 Issue 4
July-August 2025

Submit your research paper

Indexing Partners
Academia Advanced Sciences Index Bielefeld Academic Search Engine CiteSeer DRJI Google Scholar Independent Search Engine & Directory Network ISI (International Scientific Indexing) Issuu Mendeley Research Networks
RefSeek ResearcherId - Thomson Reuters ResearchGate Scirus Scribd Semantic Scholar UTeM - Universiti Teknikal Malaysia Melaka Wiki for Call for Papers WorldCat Zenodo

Speech and Language Disorders in Children with Klinefelter Syndrome: A Review Study

Author(s) Ms. Mansi Mahesh Doshi, Mr. Sushant Gupta
Country India
Abstract Klinefelter syndrome is increasingly diagnosed in childhood, with many boys exhibiting speech and language difficulties throughout development. Studies have shown that most children with this syndrome have some communication impairments. Common findings in speech and language assessments include delayed oromotor milestones, notably poor suckling and babbling, as well as persistent articulation and phonological errors. Receptive language generally surpasses expressive vocabulary and grammar, but deficits in syntactic production, word-finding, and auditory memory are typical. Pragmatic impairments—such as challenges with conversational reciprocity, figurative language, and social language use—are also common in children with this syndrome. These issues tend to worsen as academic and social demands increase. Proposed mechanisms include X-linked gene dosage effects on brain development (e.g., neuroligin-neurexin pathways) and early androgen deficiency. A variety of standardized tools—such as Bayley Scales, vocabulary and grammar assessments, and pragmatic checklists—are used to document these challenges. Early markers like hypotonia, feeding difficulties, and delayed first words should prompt genetic evaluation since early speech-language therapy can improve outcomes if delays are detected promptly. This review covers case reports and cohort studies of KS from infancy through adolescence, summarizing phonological, articulatory, expressive and receptive language, and pragmatic profiles; discussing potential neurodevelopmental mechanisms; and highlighting assessment strategies and early intervention options.
Keywords KS: Klinefelter Syndrome
Field Medical / Pharmacy
Published In Volume 7, Issue 4, July-August 2025
Published On 2025-08-03
DOI https://doi.org/10.36948/ijfmr.2025.v07i04.52852
Short DOI https://doi.org/g9vzmr
View / Download PDF File

Share this



E-ISSN 2582-2160
CrossRef

CrossRef DOI is assigned to each research paper published in our journal.

IJFMR DOI prefix is
10.36948/ijfmr

Downloads
Research Paper Format Copyright Permission Form and Undertaking Form Cover Page Vol 7 Isu 4Cover Page Vol 7 Isu 3Cover Page Vol 7 Isu 2

All research papers published on this website are licensed under Creative Commons Attribution-ShareAlike 4.0 International License, and all rights belong to their respective authors/researchers.

CC-BY-SA Open Access

About IJFMR
Fees & Payment
Current Issue
Publication Archive 		Submit Research Paper
Track Submission Status
Publication Guidelines
Publication Ethics
Peer Review & Plagiarism 		Join as a Reviewer
Editors & Reviewers
Reviewer Referral Program
Get Reviewer Membership Certi. 		Website/Journal Policies
Usage Policy
Content Policies
Privacy Policy
Contact Us +91-9687-828-838 editor@ijfmr.com