Śānto Agniḥ Mriyate: Understanding Sepsis and Multi-Organ Failure through Dhatvagni and Hormonal Regulation

Author(s)	Dr. Urvashi Sharma, Prof. Dr. Ashok Kumar Sharma
Country	India
Abstract	Ayurvedic perspective: Concept of agni 1) jatharagni 2) bhutagni 3) dhatvagni. Modern perspective: Hormonal regulation of metabolism in tissues (insulin, glucagon, thyroid, cortisol, GH, sex hormones). Rationale: Tissue-level metabolism in Ayurveda (dhatvagni) has conceptual overlap with hormone-controlled tissue energetics in modern physiology. Research gap: Lack of systematic mapping between dhatvagni and endocrine regulation. Objective: To propose a conceptual model linking dhatvagni with modern endocrine functions. Metabolism is the sum of all chemical reactions in the body, encompassing both anabolic (building) and catabolic (breaking down) processes. Hormones, secreted by various endocrine glands, serve as the body’s regulatory signals, orchestrating when and how energy is stored or utilised. Their precise balance ensures stable blood glucose, efficient energy use, and adaptation to stress, growth, and reproduction.
Keywords	Dhatvagni, Hormonal regulation, Metabolism, Endocrinology, Ayurveda, Integrative physiology
Field	Medical / Pharmacy
Published In	Volume 7, Issue 4, July-August 2025
Published On	2025-08-26
DOI	https://doi.org/10.36948/ijfmr.2025.v07i04.54470
Short DOI	https://doi.org/g9z3jn

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