International Journal For Multidisciplinary Research

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Transdermal Drug Delivery Systems: A Focused Review of Physical Methods of Permeation Enhancement

Author(s) Ms. Falgunee Dasharath Ghadi, Ms. Alfiya Ahmed Ali Rehmani, Ms. Divyata Rajendra Chavan, Ms. Fatma Anwar Khan, Ms. Krutika Navin Bhoir
Country India
Abstract The skin is the largest organ of the body and has been widely utilized as a route of drug delivery. Transdermal drug delivery systems (TDDS) offer numerous advantages over conventional routes such as bypassing hepatic first-pass metabolism, achieving controlled plasma levels, and improving patient compliance. This paper reviews the physical methods of permeation enhancement including iontophoresis, ultrasound, microneedles, and other device-assisted strategies. Schematic illustrations are included for better understanding.
Field Medical / Pharmacy
Published In Volume 7, Issue 5, September-October 2025
Published On 2025-09-19
DOI https://doi.org/10.36948/ijfmr.2025.v07i05.55640
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