International Journal For Multidisciplinary Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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“Fast Dissolving Oral Film: A Novel Drug Delivery System”

Author(s) Shrushtee Shankar Shewale, Samruddhi Kundan Rasal, Prof. Sushma Tukaram Nakhate
Country India
Abstract The development of innovative drug delivery systems has revolutionized the pharmaceutical industry, focusing on improving therapeutic efficacy and patient compliance. Among these advancements, fast dissolving oral films (FDOFs) have emerged as an effective alternative to traditional solid dosage forms such as tablets and capsules. These films dissolve quickly in the oral cavity, bypassing first-pass metabolism and enhancing drug bioavailability.Fast dissolving films are particularly beneficial for populations with difficulty swallowing, including paediatric, geriatric, and psychiatric patients. Their ease of administration, rapid onset of action, and non-invasive nature make them ideal for conditions requiring immediate drug release, such as hypertension, angina pectoris, pain management, and allergic reactions.

This review provides an in-depth analysis of the formulation, advantages, and applications of FDOFs. It discusses the methods of drug extraction, preformulation studies, medication alternatives, and case studies that highlight their effectiveness. A specific case study on Ivabradine and Bisoprolol fast dissolving films is also examined to demonstrate their potential in cardiovascular therapy. The review concludes by addressing the challenges and future prospects of fast dissolving films in modern drug delivery systems.
Keywords Keywords: Fast Dissolving Oral Films (FDOFs), Oral Drug Delivery, Buccal Absorption, Solvent Casting Method, Patient Compliance, Immediate Release Formulation, Polymer Selection, Cardiovascular Drug Delivery, Pediatric and Geriatric Therapy, Rapid Disintegration, Bioavailability Enhancement, Anatomy of Oral Mucosa, Mechanism of Drug Action, Film Formulation and Evaluation, Ivabradine and Bisoprolol Combination Therapy.
Field Medical / Pharmacy
Published In Volume 7, Issue 5, September-October 2025
Published On 2025-10-11
DOI https://doi.org/10.36948/ijfmr.2025.v07i05.57501

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