Synthesis of 8-Methyl And Methoxy Substituted 3-Amino-2-Alkyl/Aryl-3,4-Dihydro-4-Oxoquinazoline and their 2,4-DNP Derivatives

Author(s)	Dr. AKHILESH PRASAD, Dr. DILIP KUMAR
Country	India
Abstract	A series of 8-methyl and methoxy-substituted 3-amino-2-alkyl/aryl-3,4-dihydroxy-oxoquinazolines were synthesized using Klosa’s method as modified by Lal. The compounds were thoroughly characterized using standard analytical techniques. Additionally, their corresponding 2,4-dinitrophenyl (2,4-DNP) derivatives were prepared and similarly characterized to confirm structural integrity and functional group derivatization.
Keywords	4-Oxoquinazolines, Quinazoline derivatives, 3-Aminoquinazolines, 8-Methyl substitution, Methoxy substitution, 2,4-Dinitrophenyl derivatives (2,4-DNP), Klosa’s method, Lal’s modification, Benzoxazone condensation, Schiff base analogues, Structural characterization, Functional group derivatization.
Field	Chemistry
Published In	Volume 7, Issue 5, September-October 2025
Published On	2025-10-29
DOI	https://doi.org/10.36948/ijfmr.2025.v07i05.57722

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