International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Molecular Diagnosis and Viral load Assessment of HMPV from SARI & ILI cases in a tertiary care hospital, WB

Author(s) Ms. Manjusa Chowdhury, Miss Meghna Majumder, Dr. Bipasa Chakraborty, Dr. Maitreyi Bandyopadhyay, Dr. Abhra Banerjee
Country India
Abstract Human Metapneumovirus (hMPV) the second most common cause of respiratory tract infection in children after RSV and also important respiratory pathogen for adults ≥ 65 years, with increased morbidity and hospitalization in these 2 age groups. A surveillance study was done from January to June,2025 (6 months) in a tertiary care hospital of West Bengal in VRDL where respiratory samples of different age groups from different parts of West Bengal were tested for the presence of hMPV by reverse transcription polymerase chain reaction (RT-PCR). These samples were obtained from Severe Acute Respiratory Illness (SARI) cases that tested negative RT-PCR results for Influenza A and B, RSV A and B and SARS-CoV- 2. Out of 105 individuals tested, only one was positive for hMPV. An 8 month old boy with morphological Down syndrome, fever, tachypnea, cough, rhinorrhea, retractions of the chest wall and wheezing and features of heart failure were common findings. Out of hMPV-positive children, 80% patients belonged to the range of 2 months to 6 years. hMPV accounted for a small but significant proportion of respiratory-tract disease in infants and children.
Keywords hMPV, RT-PCR, Tachypnea, SARI
Field Medical / Pharmacy
Published In Volume 7, Issue 5, September-October 2025
Published On 2025-10-16
DOI https://doi.org/10.36948/ijfmr.2025.v07i05.57733
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E-ISSN 2582-2160
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