International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Reduction in Melanin Content and Hyperpigmentation Using Liposomal Tranexamic Acid A Clinical Study of AmviZome TranX Serum

Author(s) Mr. Rushabh Dharamshi, Ms. Poorna Pai, Ms. Kartiki Jadhav, Dr. Shalmali Karmarkar, Ms. Drashti Shah, Ms. Priyanka Sharma, Ms. Aditi Vichare
Country India
Abstract Abstract
Hyperpigmentation disorders such as melasma, post-inflammatory hyperpigmentation and facial dark spots are persistent, and it concerns with both cosmetic and psychological implications. Although several depigmenting agents are available, their use is often constrained by safety issues or limited effectiveness. Tranexamic acid, especially when delivered through advanced formulations, has emerged as a safer and more targeted solution. This exploratory, double- blind, randomized, placebo-controlled clinical trial evaluated the safety and efficacy of AmviZome TranX serum, a liposomal tranexamic acid formulation, in 34 adults with facial hyperpigmentation over a 60- day trial period. Assessments included instrumental measurements, dermatologist- led clinical scoring and participant feedback. The serum demonstrated meaningful improvements in skin brightness, pigmentation reduction and overall appearance as compared to placebo, while being well tolerated and free from adverse events. These findings support its potential as a safe, effective, and non-invasive option for daily management of facial hyperpigmentation.
Keywords Hyperpigmentation, Tranexamic acid, Liposomal formulation, Melasma, Clinical trial.
Published In Volume 7, Issue 5, September-October 2025
Published On 2025-10-16
DOI https://doi.org/10.36948/ijfmr.2025.v07i05.58087
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E-ISSN 2582-2160
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