International Journal For Multidisciplinary Research

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Phytochemical Analysis and Biological Activities of Curcumin

Author(s) Prachi Mishra, Sunita Mishra
Country India
Abstract Curcumin is a bright yellow phytochemical derived from the rhizome of Curcuma longa. Curcumin possesses a wide range of biological effects such as antimicrobial, anti-proliferative, antioxidant, anti-inflammatory, anti-diabetic and neuroprotective activities. Such versatility makes curcumin a promising lead compound for the development of new derivatives that may have a role in the management of numerous illnesses like cancer, diabetes and Alzheimer’s disease. These biological effects of turmeric have been attributed to its constituent curcumin that has been widely studied for its anti-diabetic, anti-obesity, anti-oxidant, wound healing and anti-cancer effects and phytochemical analysis of methanolic extract was done. As a result of extensive epidemiological, clinical, and animal studies several molecular mechanisms are emerging that elucidate multiple biological effects of curcumin. The purpose of the study was concentrated on in vitro and in vivo studies on the biological effects of Curcumin, preliminary phytochemical screening of the methanolic extract of the turmeric rhizome and determined the antioxidant activity of curcumin by employing in vitro antioxidant assays such as 1,1-diphenyl-2-picryl-hydrazyl free radical (DPPH)scavenging. The solvent extracts tested positive for the presence of bioactive constituents alkaloids, flavonoids, phenols, saponins, Terpenoids, cardiac glycosides and fixed oils and fatty acid. DPPH demonstrated total antioxidant activity.
Keywords Curcumin, Curcuma longa, Phytochemicals, Antioxidant, Anti-cancerous, Anti-diabetic, DPPH, spectrophotometer, Free Radical Scavenging.
Field Sociology > Home Science
Published In Volume 5, Issue 4, July-August 2023
Published On 2023-08-28
Cite This Phytochemical Analysis and Biological Activities of Curcumin - Prachi Mishra, Sunita Mishra - IJFMR Volume 5, Issue 4, July-August 2023. DOI 10.36948/ijfmr.2023.v05i04.5842
DOI https://doi.org/10.36948/ijfmr.2023.v05i04.5842
Short DOI https://doi.org/gsnrhc
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