Comparative Evaluation of Tamarind Leaf Extract Gel And 2% Lignocaine Gel as An Intraoral Topical Anesthetic Agent in Children.

Raghavendra Havale; Santhebachalli Prakasha Shrutha; Spoorti P Hangaragi; Shiny Raj Rajan; Kanchan M Tuppadmath; Yadlapalli Vineela Chowdary; Sai Teja Chinthalapalli

doi:10.36948/ijfmr.2025.v07i05.58573

Comparative Evaluation of Tamarind Leaf Extract Gel And 2% Lignocaine Gel as An Intraoral Topical Anesthetic Agent in Children.

Author(s)	Dr. Raghavendra Havale, Dr. Santhebachalli Prakasha Shrutha, Dr. Spoorti P Hangaragi, Dr. Shiny Raj Rajan, Dr. Kanchan M Tuppadmath, Dr. Yadlapalli Vineela Chowdary, Dr. Sai Teja Chinthalapalli
Country	India
Abstract	Background: In pediatric dentistry, local anesthetics are widely used to ensure pain-free dental procedures. Topical anesthetics are especially important in minimizing the discomfort caused by needle pricks, making dental treatments more comfortable for children. Pain-free needle prick ensure the reduced fear and anxiety throughout the dental procedures. Tamarind has been widely utilized for its therapeutic benefits in the treatment of various ailments. Tamarind is commonly utilized for various health issues, including abdominal pain, gastrointestinal disturbances, bacterial and parasitic infections, wound healing, constipation and inflammation. However, its anaesthetic efficacy have yet to be fully understood. This study aimed to compare the efficacy of tamarind leaf extract gel and lignocaine gel in reducing pain perception following intraoral injections in children aged 6-10 years. Method: This randomized, split mouth study compared the efficacy of tamarind leaf extract gel (Group A) with lignocaine gel (Group B) as pre-anesthetic agents in 38 children aged 6-10 years undergoing intraoral local anesthesia. Pain perception was assessed using the Sound, Eye and Motor (SEM) Scale and Memojis Pain Scale (MPS). Statistical analysis was performed using unpaired t-test and analysis of variance (P<0.05). Results: The study showed a significant reduction in MPS and SEM scores, with the tamarind gel group demonstrating the greatest decrease. A highly significant difference (P < 0.05) was found between the tamarind and lignocaine gel groups, indicating tamarind gel's superior pain-relieving efficacy. Conclusion: The topical application of 10% tamarind leaf extract gel was shown to be effective in alleviating pain, indicating its potential as pre-anesthetic agent.
Keywords	Anesthetics, Children, Lignocaine, Pain Perception, Tamarindus indica.
Field	Medical / Pharmacy
Published In	Volume 7, Issue 5, September-October 2025
Published On	2025-10-30
DOI	https://doi.org/10.36948/ijfmr.2025.v07i05.58573

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Comparative Evaluation of Tamarind Leaf Extract Gel And 2% Lignocaine Gel as An Intraoral Topical Anesthetic Agent in Children.

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