International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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In-Silico Analysis And Molecular Docking Of Antihistaminic Drug(Bilastine Derivative) Against H1 Receptor

Author(s) Ms. Dhanashree Dilip More, Ms. Akansha Anil Narkhede, Ms. Shrutika Kanchan Mukadam, Ms. Meeti Mahaur, Dr. Kamlesh Soni
Country India
Abstract Bilastine was substituted at its position 2 with Piperidine ring and benzene ring, which are abbreviated as BLT 1 and BLT 2 respectively. Both BLT1 and BLT 2 was docked against two different H1 receptor proteins with PDB ID 8YN2 (standard human H1 receptor) and 3RZE (Human histamine H1 receptor complexed with mini Gq). The docking score of the BLT1 and BLT2 was found to -13.4 & -13.6 Kcal/mol respectively.
Field Medical / Pharmacy
Published In Volume 7, Issue 5, September-October 2025
Published On 2025-10-27
DOI https://doi.org/10.36948/ijfmr.2025.v07i05.58900
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E-ISSN 2582-2160
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