International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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Neuro-Ocular Parkinson’s Disease Detection

Author(s) Ms. AADHIRA SULEIM A R, Ms. ELAKKIYA K, Ms. INDHUJA D, Mr. JESWIN JOE S, Dr. BENISHA R B
Country India
Abstract This study seeks to identify Parkinson's disease (PD) using neuro-ocular methods with spontaneous blink frequency and pupillary light reflex and analyzes the results using a low-cost Raspberry Pi camera and a Python-based computer vision technique. Since PD affects the blink rate and pupillary- reflexes dopaminergic and autonomic systems, diagnostic PD involves decreased frequency of blinking and delayed response of pupil constriction. For this, we built a lightweight portable device functioning in bright, uniform light, using a Raspberry Pi 4 and a Pi camera, which was able to track eye movements. The blink detection algorithm based on the eye aspect ratio and facial landmarks. The estimation of the change in size of the pupil performed using segmentation, ellipse fitting, and OpenCV. PD participants and their healthy counterparts assessed on the parameters: blink frequency, blink duration, constriction reflex latency, and maximum constriction speed. Preliminary results show that the diagnostic features of blinking and response of pupil in PD would open a new avenue for inexpensive and non-invasive PD screening.
Keywords Parkinson’s disease, blink rate, pupillary light reflex, ocular biomarkers, Raspberry Pi, Python, computer vision, OpenCV, MediaPipe, neuro-ocular screening, biomedical signal analysis.
Field Biology > Medical / Physiology
Published In Volume 7, Issue 5, September-October 2025
Published On 2025-10-30
DOI https://doi.org/10.36948/ijfmr.2025.v07i05.59055

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