International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

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The Role of Exosomes in Promoting Skin Regeneration After Facial Burns

Author(s) Ms. Margareth Yosephine Tito, Mr. Ahmad Fawzy, Ms. Ismiralda Oke Putranti
Country Indonesia
Abstract Facial burns represent a significant clinical challenge, necessitating effective treatment strategies to promote skin regeneration and minimize scarring. Recent advances in exosome research highlight their potential as a novel therapeutic modality in burn care. Exosomes, nano-sized vesicles released by various cell types, play a critical role in intercellular communication and possess the ability to deliver bioactive molecules that facilitate wound healing. This literature review discusses the biology of exosomes, their functionality in skin wound healing, and current research on their application in burn wounds. We explore the mechanisms by which exosomes mediate skin regeneration following facial burns, emphasizing their capacity to modulate inflammation, promote cell proliferation, and enhance extracellular matrix remodeling. Despite these promising benefits, variability in exosome content, inconsistent delivery mechanisms, and unresolved safety and regulatory issues still restrict their clinical translation.. Future directions include engineering exosomes for enhanced therapeutic efficacy, personalized treatment strategies, and integrating exosome therapy with existing surgical techniques. By overcoming these obstacles, exosome-based therapies have the potential to transform facial burn treatment, significantly improving patient outcomes and quality of life.
Keywords facial burns, exosomes, skin regeneration, wound healing, inflammation, extracellular matrix, therapeutic modality, personalized treatment, nano-vesicles, clinical application
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-11-09
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.59313
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E-ISSN 2582-2160
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