International Journal For Multidisciplinary Research

E-ISSN: 2582-2160     Impact Factor: 9.24

A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 6 (November-December 2025) Submit your research before last 3 days of December to publish your research paper in the issue of November-December.

Multimorbidity: The New Frontier in Internal Medicine

Author(s) Dr. Simon Purvez Grant
Country India
Abstract Multimorbidity, defined as the coexistence of multiple chronic or acute disorders in a single individual, is emerging as one of the most challenging aspects of modern internal medicine. In younger patients, its presentation can be particularly complex—often blurring diagnostic lines between primary and secondary diseases. This case report highlights a diagnostically intricate presentation of Muscle-Specific Kinase (MuSK)-positive Myasthenia Gravis in a young patient who initially presented with severe pneumonitis and respiratory failure.

Case Summary:
A young male, previously obese with significant recent weight loss, presented with acute respiratory failure secondary to fulminant pneumonitis. Despite optimal antimicrobial and ventilatory management, the patient exhibited persistent CO₂ retention and ventilatory muscle weakness. Further evaluation revealed MuSK-positive Myasthenia Gravis with concurrent nutritional cardiomyopathy and esophageal ulcerations—representing a classic example of multimorbidity that required coordinated multidisciplinary care.

Conclusion:
This case underscores the diagnostic complexity of multimorbidity in young adults and emphasizes the importance of integrating neuromuscular evaluation in patients with persistent hypercapnia despite pulmonary recovery.
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-11-21
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.60791
Short DOI https://doi.org/hbb4hv

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