International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal
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Volume 7 Issue 6
November-December 2025
Indexing Partners
Multimorbidity: The New Frontier in Internal Medicine
| Author(s) | Dr. Simon Purvez Grant |
|---|---|
| Country | India |
| Abstract | Multimorbidity, defined as the coexistence of multiple chronic or acute disorders in a single individual, is emerging as one of the most challenging aspects of modern internal medicine. In younger patients, its presentation can be particularly complex—often blurring diagnostic lines between primary and secondary diseases. This case report highlights a diagnostically intricate presentation of Muscle-Specific Kinase (MuSK)-positive Myasthenia Gravis in a young patient who initially presented with severe pneumonitis and respiratory failure. Case Summary: A young male, previously obese with significant recent weight loss, presented with acute respiratory failure secondary to fulminant pneumonitis. Despite optimal antimicrobial and ventilatory management, the patient exhibited persistent CO₂ retention and ventilatory muscle weakness. Further evaluation revealed MuSK-positive Myasthenia Gravis with concurrent nutritional cardiomyopathy and esophageal ulcerations—representing a classic example of multimorbidity that required coordinated multidisciplinary care. Conclusion: This case underscores the diagnostic complexity of multimorbidity in young adults and emphasizes the importance of integrating neuromuscular evaluation in patients with persistent hypercapnia despite pulmonary recovery. |
| Field | Medical / Pharmacy |
| Published In | Volume 7, Issue 6, November-December 2025 |
| Published On | 2025-11-21 |
| DOI | https://doi.org/10.36948/ijfmr.2025.v07i06.60791 |
| Short DOI | https://doi.org/hbb4hv |
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E-ISSN 2582-2160
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