International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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REVIEW ON APOPTOSIS PATHWAY AND ITS ROLE IN HEALTH

Author(s) Mr. Kalpesh Prakash Damahe, Mr. Karnal Sanjay Bhajipale, Mr. Ritesh Vijay Nanhore, Mr. Vishal Chatur Ramteke
Country India
Abstract Apoptosis, or programmed cell death, is a natural process that helps our body to get rid of cells that are no longer needed. It plays a vital role in the normal growth and function of multicellular organisms. When the control of cell death goes wrong, it can lead to a range of health problems, including cancer, autoimmune diseases, and degenerative disorders. Apoptosis can be triggered in different ways either by signals from inside the cell or by external cues, such as the activation of “death receptors” on the cell surface. Regardless of how it starts, all pathways eventually activate the same core machinery that carries out cell destruction. This machinery relies on a group of enzymes called caspases, which break down proteins at specific sites. Once activated, the cell is systematically dismantled i.e. essential proteins are broken down, DNA is fragmented, and neighbouring cells clean up the remains through a process called phagocytosis. This review explores what we currently know about how apoptosis is regulated, highlights key unanswered questions, and determine its role in our human body.
Keywords Medication delivery, Bioavailability, Targeted therapy, Regulated release, Pharmaceutical nanotechnology, Nanoparticles
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-11-19
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.60816
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E-ISSN 2582-2160
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