International Journal For Multidisciplinary Research

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A Widely Indexed Open Access Peer Reviewed Multidisciplinary Bi-monthly Scholarly International Journal

Call for Paper Volume 7, Issue 6 (November-December 2025) Submit your research before last 3 days of December to publish your research paper in the issue of November-December.

"In-Vitro Evaluation of the Antibacterial Activity of Iodium and Its Potencies (30 and 200) Against Escherichia coli"

Author(s) Dr. PARVATHY B MENON, Dr. BISMIL JOHN JACOB, Prof. Dr. KRISHNAKUMARIAMMA C. R, Prof. Dr. WINSTON VARGHEESE V
Country India
Abstract Escherichia coli (E. coli), a gram-negative bacillus typically found as a harmless component of the intestinal microbiota, can under certain conditions give rise to significant intestinal and extraintestinal infections. The global rise of antimicrobial resistance—particularly among multidrug-resistant E. coli strains—poses a major threat to biomedical practice, with reported resistance rates ranging from 51.1% to 91.2% for most antibiotics, except nitrofurantoin (7.3%). In this context, homoeopathy has long explored the potential therapeutic effects of highly diluted medicines. The present study investigates the in-vitro antibacterial activity of the homoeopathic drug Iodium in 30CH and 200CH potencies against E. coli. Antibacterial susceptibility testing was performed using the Kirby–Bauer disc diffusion method on Mueller–Hinton agar, the standard medium for routine bacterial sensitivity assessments. Iodium 30CH and 200CH were tested alongside positive and negative controls. The findings indicate that Iodium 200CH produced measurable zones of inhibition, demonstrating antibacterial activity comparable to that of standard antibiotics under the experimental conditions. These results suggest that highly potentized Iodium may exert observable effects on E. coli in vitro, supporting further investigation into its potential antimicrobial properties.
Keywords In vitro, E. coli, Iodium, Kirby–Bauer method, Mueller–Hinton agar
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-11-26
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.61531
Short DOI https://doi.org/hbdrhc

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