International Journal For Multidisciplinary Research
E-ISSN: 2582-2160
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Volume 7 Issue 6
November-December 2025
Indexing Partners
Early Osteoarthritis Detection from Knee X-Rays
| Author(s) | Prof. Harshith V, Mohan Gowda L, Namish Jain A, Swapnil Divate |
|---|---|
| Country | India |
| Abstract | Millions of people worldwide suffer from osteoarthritis (OA), a degenerative joint disease for which early identification is essential to slowing progression and improving patient outcomes. Even though radiographic imaging—especially X-rays—remains the most affordable and widely available diagnostic method, doctors sometimes struggle to spot minor alterations in the early stages (Kellgren–Lawrence grades 0–1). Recent advances in deep learning and artificial intelligence (AI) create new opportunities for automated early OA identification and grading on radiographs. This paper examines cutting-edge methods, stressing both their advantages and disadvantages. We propose a methodological overview for developing an automated system that integrates preprocessing, region-of-interest localization, and classification to improve sensitivity in early OA detection. There includes discussion of difficulties such poor generalizability across datasets, class imbalance, and interpretability problems. Finally, we outline future research initiatives, stressing the necessity of integrating radiomic biomarkers, developing clinically interpretable AI models, and obtaining larger multi-center datasets. |
| Keywords | Osteoarthritis, Knee radiograph, Early identification, Kellgren-Lawrence grades, Deep learning, Convolutional neural networks (CNN), Transfer learning, Radiomics, Medical image analysis, Explainable AI, Radiographic images, Machine learning, ROI, classification, and preprocessing. |
| Field | Medical / Pharmacy |
| Published In | Volume 7, Issue 6, November-December 2025 |
| Published On | 2025-11-24 |
| DOI | https://doi.org/10.36948/ijfmr.2025.v07i06.61534 |
| Short DOI | https://doi.org/hbcbbc |
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E-ISSN 2582-2160
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