International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Volume 7 Issue 6
November-December 2025

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Effects of Dietary Immunostimulants on the Serum Chemistry of Catla Catla Challenged with Aeromonas Hydrophila

Author(s) Mr. Eisay Ali Alkasak, Prof. K. Sunita
Country India
Abstract This study assessed the immunomodulatory activities of dietary immunostimulants in Catla catla infected with Aeromonas hydrophila. Diets supplemented with vitamin C, vitamin E, chitin, chitosan, and levamisole were given orally. Serum biochemical and immunological parameters, including total protein, albumin, globulin, A/G ratio, IgM, lysozyme activity (LA), alkaline phosphatase (AKP), and aspartate aminotransferase (AST), were analyzed under normal and pathogen-infected conditions to determine innate and adaptive immunity. Supplementation with immunostimulants significantly (p < 0.05) elevated serum fractions of proteins, IgM levels, and lysozyme activity compared to the controls. Vitamin E and levamisole significantly increased albumin, globulin, and A/G ratio, indicative of improved immune stability. Increased activities of AKP and AST levels revealed activated macrophage functions and metabolic defense mechanisms. Generally, levamisole and vitamin E promoted both innate and adaptive immunity effectively, confirming their usefulness as aquaculture dietary supplements to enhance disease resistance, prevent antibiotic overuse, and ensure sustainable fish health management.
Keywords Catla Catla, Immunostimulant, Serum biochemistry, Aeromonas hydrophilla
Field Biology > Zoology
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-11-27
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.61807
Short DOI https://doi.org/hbdr68
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