International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Volume 7 Issue 6
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Leap of Relief: Frog Based Exploration of Herbal Analgesia through Polyalthia Longifolia

Author(s) P.Mary Grace, A.Kamakshidevi, G.Nagadeepika, M.Harshitha, S.Nageswararao
Country India
Abstract The current study looks at the analgesic potential of Polyalthia longifolia bark extract and compares its efficacy to the standard medicine acetyl salicylic acid, utilising Rana tigrina (Indian bullfrog) as an experimental model. The bark extract of Polyalthaia. longifolia was produced using appropriate solvent extraction procedures and delivered in graduated quantities. Analgesic activity was determined by measuring the frog's response to nociceptive stimuli such as acetic acid (aspirin)-induced pain reflexes and thermal stimuli using established pharmacological techniques. The results showed that Polyalthia longifolia bark extract significantly reduced pain responses in a dose-dependent manner. At greater doses, the impact was comparable to aspirin, indicating the presence of analgesic-like bioactive chemicals. The results indicate that Polyalthia longifolia bark has promising analgesic potential.It could be used as a natural alternative or supplement to conventional nonsteroidal anti-inflammatory medicines (NSAIDs). More research into the separation and characterisation of active ingredients is needed to understand the underlying mechanism of action.
Keywords Polyalthia longifolia, analgesic activity, aspirin,Rana tigrina, Bark extract, phytochemical screening.
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-11-28
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.62255
Short DOI https://doi.org/hbdsjs
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