Effect of 50% Saponin-Standardized Fenugreek Extract on Free Testosterone: An 8-Week Randomized Controlled Trial

Author(s)	Dr. Ramana V Krishnan, Dr. Kavitha PS
Country	India
Abstract	his study investigates the endocrine effects of a standardized fenugreek (Trigonella foenum-graecum) extract containing 50% saponins on free testosterone levels in healthy adult males. Forty-two participants were randomly assigned to a fenugreek supplementation group (600 mg/day) or placebo for eight weeks. Hormonal biomarkers including free testosterone, total testosterone, SHBG, LH, and FSH were measured at baseline and week 8. The fenugreek group demonstrated a significant increase in free testosterone (+18.7%), accompanied by a 6.2% reduction in SHBG. Total testosterone increased modestly (+6.4%) but remained within physiological norms. No significant hormonal fluctuations occurred in the placebo group. The findings suggest that 50% saponin fenugreek extract enhances androgen bioavailability primarily by modulating SHBG.
Keywords	Free Testosterone
Field	Business Administration
Published In	Volume 7, Issue 6, November-December 2025
Published On	2025-12-05
DOI	https://doi.org/10.36948/ijfmr.2025.v07i06.62728

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