International Journal For Multidisciplinary Research

E-ISSN: 2582-2160   •   Impact Factor: 9.24

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Evaluation of prescribing pattern and impact of polypharmacy in geriatric patients with chronic kidney disease

Author(s) Prof. Dr. SHIVASHANKAR V V, Ms. SHRIKA SAKTHIVELU V S
Country India
Abstract Chronic Kidney Disease (CKD) is a progressive condition affecting about 10% of the global adult population and is projected to become the fifth leading cause of death by 2040. Geriatric CKD patients are highly susceptible to polypharmacy due to multiple comorbidities such as hypertension and diabetes, increasing the risk of potentially inappropriate medications (PIMs), drug interactions, and adverse effects. This prospective observational study evaluated prescribing patterns, polypharmacy prevalence, and PIM use among 80 geriatric CKD patients in a tertiary care hospital using the 2023 AGS Beers Criteria. Males constituted 71.25% of participants, and most were aged 65–74 years. Hypertension (75%) and diabetes mellitus (68.75%) were the leading comorbidities. Over half of the prescriptions (51.25%) included at least one PIM, with aspirin, clonidine, prazosin, and enoxaparin being most frequent. Polypharmacy was common, with many patients receiving more than ten drugs. Despite short hospital stays (2–4 days), inappropriate prescribing remained high, mainly due to lack of renal dose adjustment. The study emphasizes the need for rational prescribing, regular medication audits, and clinical pharmacist involvement to minimize PIMs and improve therapeutic outcomes in elderly CKD patients.
Keywords CKD, Geriatric, Polypharmacy, Beers Criteria, PIMs, Prescribing Pattern.
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-12-11
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.63024
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E-ISSN 2582-2160
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