International Journal For Multidisciplinary Research

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An Intriguing Medical Case Report: Diplopia and Rashes Caused by Levosimendan

Author(s) Dr. Pratik Mohan Bangi, Dr. Vanlawmpuii C, Dr. Balakeshwa Ramaiah, Dr. Thabit Ahmed
Country India
Abstract Levosimendan, a calcium sensitizer and inodilator, is increasingly used in the peri-operative management of cardiac surgery patients. Although its commonly reported adverse drug reactions (ADRs) include headache, hypotension, hypokalaemia, and arrhythmias, rare reactions are not well documented.We report the case of a 42-year-old male with ischemic heart disease and unstable angina who was scheduled for coronary artery bypass grafting (CABG). As part of the pre-operative optimization protocol, Levosimendan infusion (12.5 mg in 500 mL NS) was initiated 24 hours prior to surgery. Within five minutes of infusion, the patient developed sudden-onset diplopia and localized rashes over the fingers. The infusion was immediately discontinued, following which the diplopia resolved within five minutes and the rashes subsided completely within two days. Concomitant medications included pantoprazole and zolpidem, with no known interactions.This case highlights two uncommon ADRs—diplopia and cutaneous rash—associated with Levosimendan administration. Early recognition and prompt discontinuation of the drug are essential to prevent further complications. Clinicians should be aware of these potential reactions to ensure timely management and improve patient safety.
Keywords Keywords: Levosimendan, Diplopia, Rash, ADR, Case report
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-12-23
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.63308
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E-ISSN 2582-2160
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