International Journal For Multidisciplinary Research

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Combined Effect of Musa paradisiaca & Cinnamomum zeylanicum for Hepatoprotective Activity

Author(s) Mr. Prasad Vishvambhar Kadam, Dr. Atul Ramchandra Chopade, Dr. Suresh G. Killedar
Country India
Abstract Hepatic disorders, including hepatotoxicity and liver injury, are a major global health concern resulting from drug overdose, alcohol, environmental toxins, and infectious agents. Conventional hepatoprotective drugs often have limited efficacy and potential side effects, which has driven interest toward natural alternatives. Musa paradisiaca (banana) and Cinnamomum zeylanicum (true cinnamon) are widely recognized in traditional medicine for their liver-protective properties. Musa paradisiaca contains flavonoids, polyphenols, carotenoids, vitamins, and dopamine, which exert antioxidant, anti-inflammatory, and hepatocyte-regenerative effects. Cinnamomum zeylanicum is rich in cinnamaldehyde, eugenol, polyphenols, and essential oils that reduce oxidative stress, inhibit inflammatory pathways, and stabilize hepatocyte membranes. The combination of these two botanicals offers a synergistic effect by targeting multiple mechanisms, including free radical scavenging, inhibition of lipid peroxidation, reduction of inflammatory mediators, enhancement of detoxifying enzymes, and promotion of liver tissue regeneration. This review comprehensively examines the pharmacological rationale, mechanistic insights, and therapeutic potential of combining Musa paradisiaca and Cinnamomum zeylanicum as a natural hepatoprotective strategy, emphasizing the need for further experimental validation and clinical studies to develop standardized formulations.
Keywords Musa paradisiaca, Cinnamomum zeylanicum, Hepatoprotection, Antioxidant, Anti-inflammatory, Herbal formulation, Liver injury, Synergistic effect
Field Medical / Pharmacy
Published In Volume 7, Issue 6, November-December 2025
Published On 2025-12-17
DOI https://doi.org/10.36948/ijfmr.2025.v07i06.63666
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E-ISSN 2582-2160
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