Pulsatile Drug Delivery System- An Systematic Review.

Ratikesh Ashokrao Wawarkar; Swapnil Ramchandra Dudhakohar; Shraddha Raju Wasnik; Tejal Sunil Nimbarte

doi:10.36948/ijfmr.2025.v07i06.63863

Pulsatile Drug Delivery System- An Systematic Review.

Author(s)	Mr. Ratikesh Ashokrao Wawarkar, Mr. Swapnil Ramchandra Dudhakohar, Ms. Shraddha Raju Wasnik, Ms. Tejal Sunil Nimbarte
Country	India
Abstract	Interest in drug delivery systems has grown over the past few decades due to developments in pharmaceutical technologies. Due to the inherent difficulties in the discovery and development process, pharmaceutical galenic research now concentrates on developing more effective drug delivery systems employing already-existing compounds rather than exploring novel drug discovery. The development of Pulsatile medication Delivery Systems is motivated by the need to treat disorders that require a periodic pulse of therapeutic concentration rather than constant medication levels. The market's pulsatile medication delivery systems. The following describes a number of commercial pulsatile drug delivery systems, including Pulsincap, Diffucap®, 3-Dimensional Printing®, CODAS®, OROS®, PULSYS, Diffutab, Orbexa, and Minitab: For illnesses that exhibit circadian rhythms or time-dependent symptom fluctuations, pulsatile medication delivery methods are particularly helpful. Asthma, heart problems, hormone abnormalities, and specific kinds of discomfort are a few examples. In these circumstances, pulsatile delivery can release medications at particular times when the disease is at its peak or when the body's normal cycles are upset. This tactic can improve medication effectiveness and lessen negative effects that are frequently brought on by continuous or non-specific drug release. In general, the targeted and time-controlled release of therapeutic medicines requires pulsatile drug delivery systems. Compared to traditional drug administration techniques, these systems have a number of advantages, including increased patient compliance, reduced adverse effects, and higher therapeutic efficacy. To properly enhance pulsatile systems and apply them to clinical practice, however, further research and development work is needed.
Keywords	Pulsatile Drug Delivery Systems, Galenic Research, Circadian Rhythms Time-Controlled Release, Therapeutic Efficacy
Field	Medical / Pharmacy
Published In	Volume 7, Issue 6, November-December 2025
Published On	2025-12-19
DOI	https://doi.org/10.36948/ijfmr.2025.v07i06.63863

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Pulsatile Drug Delivery System- An Systematic Review.

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