Inflammatory Biomarkers in the ICU: Postoperative Kinetics of C-Reactive Protein After Cardiac Surgery With Cardiopulmonary Bypass

Author(s)	Dr. Abderrahim Essalama, Prof. Dr. Ali Derkaoui, Dr. Houda Benmlih, Khatouf Mohamed, Shimi Abdelkarim, Bichri Ibrahim, Majdoub Amine
Country	Morocco
Abstract	Introduction: Cardiac surgery with cardiopulmonary bypass (CPB) triggers a major inflammatory response. This study evaluated postoperative C-reactive protein (CRP) kinetics and their association with complications. Methods: Retrospective study of adults admitted to ICU after cardiac surgery with CPB in 2023. CRP was measured preoperatively, at 24h, 48h, and postoperative day 7 (POD7). Results: Among 88 patients, CRP peaked at 216.9 mg/L at 48h. Complications occurred in 55.7% of cases. Only POD7 CRP remained significantly higher in complicated patients (80.2 vs 62.8 mg/L; p≈0.03). Conclusion: Persistent elevation of CRP on POD7 is associated with postoperative complications and may improve risk stratification after cardiac surgery.
Keywords	CRP; cardiopulmonary bypass; cardiac surgery; inflammation; postoperative complications; intensive care
Field	Medical / Pharmacy
Published In	Volume 7, Issue 6, November-December 2025
Published On	2025-12-28
DOI	https://doi.org/10.36948/ijfmr.2025.v07i06.64326

About IJFMR Fees & Payment Current Issue Publication Archive	Submit Research Paper Track Submission Status Publication Guidelines Publication Ethics Peer Review & Plagiarism	Join as a Reviewer Editors & Reviewers Reviewer Referral Program Get Reviewer Membership Certi.	Website/Journal Policies Usage Policy Content Policies Privacy Policy

Contact Us		+91-9687-828-838	editor@ijfmr.com

International Journal For Multidisciplinary Research